PDB entry 6hgx

View 6hgx on RCSB PDB site
Description: Soluble epoxide hydrolase in complex with 1-(4-((4-(tert-butyl)morpholin-2-yl)methoxy)phenyl)-3-cyclohexylurea
Class: hydrolase
Keywords: Inhibitor, Complex, sEH, Hydrolase
Deposited on 2018-08-23, released 2019-07-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-24, with a file datestamp of 2021-02-19.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHX2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hgxa_
  • Heterogens: MG, G3T, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hgxA (A:)
maslntpaplptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqi
palaqagyrvlamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwgg
mlvwymalfypervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaele
qnlsrtfkslfrasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksg
frgplnwyrnmernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrgh
iedcghwtqmdkptevnqilikwldsdarnppvvskmllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6hgxA (A:)
ptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrv
lamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfy
pervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfksl
frasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrn
mernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqm
dkptevnqilikwldsdar