PDB entry 6hgq

View 6hgq on RCSB PDB site
Description: Crystal Structure of Human APRT wild type in complex with Hypoxanthine, PRPP and Mg2+
Class: transferase
Keywords: Rossman fold, transferase
Deposited on 2018-08-23, released 2019-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Adenine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: APRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hgqa_
  • Chain 'B':
    Compound: Adenine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: APRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hgqb_
  • Chain 'C':
    Compound: Adenine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: APRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hgqc_
  • Chain 'D':
    Compound: Adenine phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: APRT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6hgqd_
  • Heterogens: HPA, MG, PRP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hgqA (A:)
adselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyi
agldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepgq
rvvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6hgqB (B:)
adselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyi
agldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepgq
rvvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye

    Sequence, based on observed residues (ATOM records): (download) 
    >6hgqB (B:)
selqlveqrirsfpdfpvvfrdispvlkdpasfraaigllarhlkathggridyiaglds
rgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepgqrvvvv
ddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6hgqC (C:)
adselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyi
agldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepgq
rvvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6hgqD (D:)
adselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyi
agldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepgq
rvvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye

    Sequence, based on observed residues (ATOM records): (download) 
    >6hgqD (D:)
selqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyiag
ldsrgflfgpslaqelglgcvlirkrgklpgptlwasysleygkaeleiqkdalepgqrv
vvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye