PDB entry 6heu

View 6heu on RCSB PDB site
Description: Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with the NVP-BHG712 derivative AT058
Class: transferase
Keywords: Inhibitor, Complex, Protein Tyrosine Kinase, Transferase
Deposited on 2018-08-20, released 2019-08-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-A receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA2, ECK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6heua_
  • Heterogens: G0N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6heuA (A:)
gdpnqavlkftteihpscvtrqkvigagefgevykgmlktssgkkevpvaiktlkagyte
kqrvdflgeagimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvl
qlvgmlrgiaagmkylanmnyvhrdlaarnilvnsnlvckvsdfglsrvleddpeatytt
sggkipirwtapeaisyrkftsasdvwsfgivmwevmtygerpywelsnhevmkaindgf
rlptpmdcpsaiyqlmmqcwqqerarrpkfadivsildklirapdslktladfdprvsir
lpstsg

    Sequence, based on observed residues (ATOM records): (download) 
    >6heuA (A:)
avlkftteihpscvtrqkvigagefgevykgmlktkevpvaiktlkagytekqrvdflge
agimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvlqlvgmlrgi
aagmkylanmnyvhrdlaarnilvnsnlvckvsdfglspirwtapeaisyrkftsasdvw
sfgivmwevmtygerpywelsnhevmkaindgfrlptpmdcpsaiyqlmmqcwqqerarr
pkfadivsildklirapdslktladfdprvsirlp