PDB entry 6he2

View 6he2 on RCSB PDB site
Description: crystal structure of an open conformation of 2-hydroxyisobutyryl-coa ligase (hcl) in complex with 2-hib-amp and coa
Deposited on 2018-08-20, released 2019-08-28
The last revision was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-hydroxyisobutyryl-CoA synthetase
    Species: Aquincola tertiaricarbonis [TaxId:391953]
    Gene: hcl
    Database cross-references and differences (RAF-indexed):
    • Uniprot I3VE75 (11-End)
      • expression tag (6-10)
  • Chain 'B':
    Compound: 2-hydroxyisobutyryl-CoA synthetase
    Species: Aquincola tertiaricarbonis [TaxId:391953]
    Gene: hcl
    Database cross-references and differences (RAF-indexed):
    • Uniprot I3VE75 (11-End)
      • expression tag (8-10)
  • Heterogens: AMP, 8LE, COA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6he2A (A:)
mashhhhhhsgmeewnfpveydenylppadsrywfprretmpaaerdkailgrlqqvcqy
awehapfyrrkweeagfqpsqlksledfearvpvvkktdlresqaahppfgdyvcvpnse
ifhvhgtsgttgrptafgigradwraianaharimwgmgirpgdlvcvaavfslymgswg
alagaerlrakafpfgagapgmsarlvqwldtmkpaafygtpsyaihlaevareeklnpr
nfglkclffsgepgasvpgvkdrieeaygakvydcgsmaemspfmnvagteqsndgmlcw
qdiiytevcdpanmrrvpygqrgtpvythlertsqpmirllsgdltlwtndenpcgrtyp
rlpqgifgriddmftirgeniypseidaalnqmsgyggehrivitresamdelllrveps
esvhaagaaaletfrteashrvqtvlgvrakvelvapnsiartdfkarrviddrevfral
nqqlqssagsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6he2A (A:)
hhhsgmeewnfpveydenylppadsrywfprretmpaaerdkailgrlqqvcqyawehap
fyrrkweeagfqpsqlksledfearvpvvkktdlresqaahppfgdyvcvpnseifhvhg
tsrptafgigradwraianaharimwgmgirpgdlvcvaavfslymgswgalagaerlra
kafpfgagapgmsarlvqwldtmkpaafygtpsyaihlaevareeklnprnfglkclffs
gepgasvpgvkdrieeaygakvydcgsmaemspfmnvagteqsndgmlcwqdiiytevcd
panmrrvpygqrgtpvythlertsqpmirllsgdltlwtndenpcgrtyprlpqgifgri
ddmftirgeniypseidaalnqmsgyggehrivitrmdelllrvepsesvhaagaaalet
frteashrvqtvlgvrakvelvapnsiartdfkarrvidd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6he2B (B:)
mashhhhhhsgmeewnfpveydenylppadsrywfprretmpaaerdkailgrlqqvcqy
awehapfyrrkweeagfqpsqlksledfearvpvvkktdlresqaahppfgdyvcvpnse
ifhvhgtsgttgrptafgigradwraianaharimwgmgirpgdlvcvaavfslymgswg
alagaerlrakafpfgagapgmsarlvqwldtmkpaafygtpsyaihlaevareeklnpr
nfglkclffsgepgasvpgvkdrieeaygakvydcgsmaemspfmnvagteqsndgmlcw
qdiiytevcdpanmrrvpygqrgtpvythlertsqpmirllsgdltlwtndenpcgrtyp
rlpqgifgriddmftirgeniypseidaalnqmsgyggehrivitresamdelllrveps
esvhaagaaaletfrteashrvqtvlgvrakvelvapnsiartdfkarrviddrevfral
nqqlqssagsawshpqfek

    Sequence, based on observed residues (ATOM records):
    >6he2B (B:)
hsgmeewnfpveydenylppadsrywfprretmpaaerdkailgrlqqvcqyawehapfy
rrkweeagfqpsqlksledfearvpvvkktdlresqaahppfgdyvcvpnseifhvhgts
grptafgigradwraianaharimwgmgirpgdlvcvaavfslymgswgalagaerlrak
afpfgagapgmsarlvqwldtmkpaafygtpsyaihlaevareeklnprnfglkclffsg
epgasvpgvkdrieeaygakvydcgsmaemspfmnvagteqsndgmlcwqdiiytevcdp
anmrrvpygqrgtpvythlertsqpmirllsgdltlwtndenpcgrtyprlpqgifgrid
dmftirgeniypseidaalnqmsgyggehrivlllrvepsesvhaagaaaletfrteash
rvqtvlgvra