PDB entry 6hdr

View 6hdr on RCSB PDB site
Description: human dyrk2 bound to curcumin
Deposited on 2018-08-18, released 2019-08-28
The last revision was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity tyrosine-phosphorylation-regulated kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: DYRK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q92630 (22-End)
      • expression tag (4-21)
  • Heterogens: CC9, DTD, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hdrA (A:)
mhhhhhhssgvdlgtenlyfqsmgkvkatpmtpeqamkqymqkltafehheifsypeiyf
lglnakkrqgmtggpnnggydddqgsyvqvphdhvayryevlkvigkgsfgqvvkaydhk
vhqhvalkmvrnekrfhrqaaeeirilehlrkqdkdntmnvihmlenftfrnhicmtfel
lsmnlyelikknkfqgfslplvrkfahsilqcldalhknriihcdlkpenillkqqgrsg
ikvidfgsscyehqrvytyiqsrfyrapevilgarygmpidmwslgcilaelltgypllp
gedegdqlacmiellgmpsqklldaskraknfvsskgypryctvttlsdgsvvlnggrsr
rgklrgppesrewgnalkgcddplfldflkqclewdpavrmtpgqalrhpwlrrrlpkpp
tgektsvkr

    Sequence, based on observed residues (ATOM records):
    >6hdrA (A:)
hhhssgvdlgtenlyfqsmgkvkatpmtpeqamkqymqkltafehheifsypeiyflgln
akkrqgmtggpnnggydddqgsyvqvphdhvayryevlkvigkgsfgqvvkaydhkvhqh
valkmvrnekrfhrqaaeeirilehlrkqdkdntmnvihmlenftfrnhicmtfellsmn
lyelikknkfqgfslplvrkfahsilqcldalhknriihcdlkpenillkqqgrsgikvi
dfgsscyehqrvytyiqsrfyrapevilgarygmpidmwslgcilaelltgypllpgede
gdqlacmiellgmpsqklldaskraknfvsskgypryctvttlsdvvlnggrsrrgklrg
ppesrewgnalkgcddplfldflkqclewdpavrmtpgqalrhpwlr