PDB entry 6hdc

View 6hdc on RCSB PDB site
Description: crystal structure of the potassium channel mttmem175 t38a variant in complex with a nanobody-mbp fusion protein
Deposited on 2018-08-17, released 2019-08-28
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nanobody,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: malE, b4034, JW3994
    Database cross-references and differences (RAF-indexed):
    • PDB 6HDC (Start-121)
    • Uniprot P0AEX9 (122-482)
  • Chain 'B':
    Compound: tmem175
    Species: Marivirga tractuosa DSM 4126 [TaxId:643867]
    Gene: Ftrac_2467
    Database cross-references and differences (RAF-indexed):
    • Uniprot E4TN31
      • engineered mutation (38)
  • Heterogens: LMT, K, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hdcA (A:)
gpsqrqlvesggglvqpggslrlscaasgsilyfnrmgwyrqapgkqrelvaaitsgdst
nyadpvkgrftisrdnakntvylqmnslkpedtavyycnakekgwsfslydywgqgtpvt
vvklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiifwa
hdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdllp
nppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdvgv
dnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskvnyg
vtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplgava
lksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdealkd
aqtpga

    Sequence, based on observed residues (ATOM records):
    >6hdcA (A:)
qrqlvesggglvqpggslrlscaasgsilyfnrmgwyrqapgkqrelvaaitsgdstnya
dpvkgrftisrdnakntvylqmnslkpedtavyycnakekgwsfslydywgqgtpvtvvk
lviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiifwahdr
fggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdllpnpp
ktweeipaldkelkakgksalmfnlqepyftwpliaadgnagakagltflvdliknkhmn
adtdysiaeaafnkgetamtingpwawsnidtskvnygvtvlptfkgqpskpfvgvlsag
inaaspnkelakeflenylltdegleavnkdkplgavalksyeeelakdpriaatmenaq
kgeimpnipqmsafwyavrtavinaasgrqtvdealkdaqt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hdcB (B:)
msrkvfetvvglnpnfsfrgkqqtrietfsdavfalaiallvlsstipetfedlwasmrd
vipfaicvaliiviwyqhyifflkyglqdkvtillntillfvllvyvyplkflarflsei
yggifgiietdlsrfgeyshqnlkllmvnyglgafaiflvfslmywraykmkslldlnsy
eifdtkssiianllmcsvpllsliitlidpwgnfrttilsgflyflyvpimivfgritsk
ksrrllqdalevlfq

    Sequence, based on observed residues (ATOM records):
    >6hdcB (B:)
vglnpnfsfrgkqqtrietfsdavfalaiallvlsstipetfedlwasmrdvipfaicva
liiviwyqhyifflkyglqdkvtillntillfvllvyvyplkflarflseiyggifgiie
tdlsrfgeyshqnlkllmvnyglgafaiflvfslmywraykmkslldlnsyeifdtkssi
ianllmcsvpllsliitlidpwgnfrttilsgflyflyvpimivfgritskk