PDB entry 6hd6

View 6hd6 on RCSB PDB site
Description: abl1 in complex with compound6 and imatinib (sti-571)
Class: transferase
Keywords: PHOSPHOTRANSFERASE, Inhibitor complex, TRANSFERASE
Deposited on 2018-08-17, released 2018-09-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-10-10, with a file datestamp of 2018-10-05.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase ABL1
    Species: Mus musculus [TaxId:10090]
    Gene: Abl1, Abl
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00520 (6-End)
      • expression tag (1-5)
    Domains in SCOPe 2.08: d6hd6a1, d6hd6a2
  • Chain 'B':
    Compound: Tyrosine-protein kinase ABL1
    Species: Mus musculus [TaxId:10090]
    Gene: Abl1, Abl
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00520 (6-End)
      • expression tag (2-5)
    Domains in SCOPe 2.08: d6hd6b1, d6hd6b2
  • Heterogens: CL, FYH, STI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6hd6A (A:)
gamdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmevee
flkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvlly
matqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfp
ikwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpe
gcpekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekelgkrgt

    Sequence, based on observed residues (ATOM records): (download) 
    >6hd6A (A:)
amdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkemeveeflk
eaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymat
qissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikw
tapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcp
ekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekel

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6hd6B (B:)
gamdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmevee
flkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvlly
matqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfp
ikwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpe
gcpekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekelgkrgt

    Sequence, based on observed residues (ATOM records): (download) 
    >6hd6B (B:)
mdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkmeveeflkea
avmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllymatqi
ssameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwta
peslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpek
vyelmracwqwnpsdrpsfaeihqafetmfqessisdevekel