PDB entry 6hcs

View 6hcs on RCSB PDB site
Description: crystal structure of cam-peptide complex containing azf at position 108
Deposited on 2018-08-16, released 2018-12-05
The last revision was dated 2018-12-19, with a file datestamp of 2018-12-14.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DP23
      • engineered mutation (108)
  • Chain 'B':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit beta
    Species: RATTUS NORVEGICUS, synthetic [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DP23
      • engineered mutation (108)
  • Chain 'D':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit beta
    Species: RATTUS NORVEGICUS, synthetic [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DP23
      • engineered mutation (108)
  • Chain 'F':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit beta
    Species: RATTUS NORVEGICUS, synthetic [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Calmodulin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: Calm1, Calm, Cam, Cam1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DP23
      • engineered mutation (108)
  • Chain 'H':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit beta
    Species: RATTUS NORVEGICUS, synthetic [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hcsA (A:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhxmtnlgekltde
evdemireadidgdgqvnyeefvqmmtaklegtglevlfqghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6hcsA (A:)
dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
tidfpefltmmarkeireafrvfdkdgngyisaaelrhxmtnlgekltdeevdemiread
idgdgqvnyeefvqmmt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6hcsB (B:)
lkkfnarrklkgailttmlatrnfs

    Sequence, based on observed residues (ATOM records):
    >6hcsB (B:)
fnarrklkgailttmlatr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6hcsC (C:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhxmtnlgekltde
evdemireadidgdgqvnyeefvqmmtaklegtglevlfqghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6hcsC (C:)
dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
tidfpefltmmarkmeeireafrvfdkdgngyisaaelrhxmtnlgekltdeevdemire
adidgdgqvnyeefvqmmt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6hcsD (D:)
lkkfnarrklkgailttmlatrnfs

    Sequence, based on observed residues (ATOM records):
    >6hcsD (D:)
fnarrklkgailttmlatrnf

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6hcsE (E:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhxmtnlgekltde
evdemireadidgdgqvnyeefvqmmtaklegtglevlfqghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6hcsE (E:)
dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
tidfpefltmmarkmeireafrvfdkdgngyisaaelrhxmtnlgekltdeevdemirea
didgdgqvnyeefvqmmt

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6hcsF (F:)
lkkfnarrklkgailttmlatrnfs

    Sequence, based on observed residues (ATOM records):
    >6hcsF (F:)
fnarrklkgailttmlat

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6hcsG (G:)
madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhxmtnlgekltde
evdemireadidgdgqvnyeefvqmmtaklegtglevlfqghhhhhh

    Sequence, based on observed residues (ATOM records):
    >6hcsG (G:)
dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
tidfpefltmmarkmeireafrvfdkdgngyisaaelrhxmtnlgekltdeevdemirea
didgdgqvnyeefvqmmt

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6hcsH (H:)
lkkfnarrklkgailttmlatrnfs

    Sequence, based on observed residues (ATOM records):
    >6hcsH (H:)
fnarrklkgailttmlat