PDB entry 6hc8

View 6hc8 on RCSB PDB site
Description: factor inhibiting hif (fih) in complex with zinc, nog and trpa1 (313- 339)
Deposited on 2018-08-14, released 2019-08-28
The last revision was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hypoxia-inducible factor 1-alpha inhibitor
    Species: Homo sapiens [TaxId:9606]
    Gene: HIF1AN, FIH1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Transient receptor potential cation channel subfamily A member 1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, OGA, SO4, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6hc8A (A:)
smaataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeeliene
epvvltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsn
reemkfhefveklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgw
gqltsnllligmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrq
sqvdfdnpdyerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykg
aptpkrieyplkahqkvaimrniekmlgealgnpqevgpllntmikgryn

    Sequence, based on observed residues (ATOM records):
    >6hc8A (A:)
maavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvlt
dtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkf
hefveklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsn
llligmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfd
npdyerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkr
ieyplkahqkvaimrniekmlgealgnpqevgpllntmikgryn

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6hc8E (E:)
lhraslfdhheladylisvgadinkid

    Sequence, based on observed residues (ATOM records):
    >6hc8E (E:)
ladylisvgadinkid