PDB entry 6h78

View 6h78 on RCSB PDB site
Description: e1 enzyme for ubiquitin like protein activation.
Deposited on 2018-07-30, released 2018-10-31
The last revision was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: Ubiquitin-like modifier-activating enzyme 5
    Species: Homo sapiens [TaxId:9606]
    Gene: UBA5, UBE1DC1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ATP, MG, ZN, EDO, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6h78A (A:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78A (A:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektgvcaaslpttmgvvagilvqnvlkfllnfgtv
sfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaal

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6h78B (B:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78B (B:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanegvcaaslpttmgvvagilvqnvlkfllnfgtvsfyl
gynamqdffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6h78C (C:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78C (C:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6h78D (D:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78D (D:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacappegvcaaslpttmgvvagilvqnvlkfllnfgtvsfylgynamq
dffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6h78E (E:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78E (E:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6h78F (F:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78F (F:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacappgvcaaslpttmgvvagilvqnvlkfllnfgtvsfylgynamqd
ffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6h78G (G:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78G (G:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanvcaaslpttmgvvagilvqnvlkfllnfgtvsfylgy
namqdffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6h78H (H:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78H (H:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektgvcaaslpttmgvvagilvqnvlkfllnfgtv
sfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkv

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6h78I (I:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78I (I:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlcaaslpttmgvvagilvqnvlkfllnfgtvs
fylgynamqdffptmsmkpnpqcddrncrkqqeeykkkva

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6h78J (J:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78J (J:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanregvcaaslpttmgvvagilvqnvlkfllnfgtvsfy
lgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6h78K (K:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78K (K:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaegvcaaslpttmgvvagilvqnvlkfllnfgtvsfylgy
namqdffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6h78L (L:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78L (L:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektvcaaslpttmgvvagilvqnvlkfllnfgtvs
fylgynamqdffptmsmkpnpqcddrncrkqqeeykkkva

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6h78M (M:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78M (M:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacappvcaaslpttmgvvagilvqnvlkfllnfgtvsfylgynamqdf
fptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6h78N (N:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78N (N:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'O':
    Sequence, based on SEQRES records:
    >6h78O (O:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78O (O:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacappgvcaaslpttmgvvagilvqnvlkfllnfgtvsfylgynamqd
ffptmsmkpnpqcddrncrkqqeeykkkvaa

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6h78P (P:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaalpkqeviqeeeeii

    Sequence, based on observed residues (ATOM records):
    >6h78P (P:)
grvriekmssevvdsnpysrlmalkrmgivsdyekirtfavaivgvggvgsvtaemltrc
gigklllfdydkvelanmnrlffqphqaglskvqaaehtlrninpdvlfevhnynittve
nfqhfmdrisnggleegkpvdlvlscvdnfearmtintacnelgqtwmesgvsenavsgh
iqliipgesacfacapplvvaanidektlkregvcaaslpttmgvvagilvqnvlkflln
fgtvsfylgynamqdffptmsmkpnpqcddrncrkqqeeykkkvaa