PDB entry 6h4h

View 6h4h on RCSB PDB site
Description: usp28 catalytic domain variant e593d in complex with ubpa
Deposited on 2018-07-21, released 2019-03-27
The last revision was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 28
    Species: Homo sapiens [TaxId:9606]
    Gene: USP28, KIAA1515
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96RU2 (1-End)
      • expression tag (0)
      • engineered mutation (445)
  • Chain 'B':
    Compound: Ubiquitin carboxyl-terminal hydrolase 28
    Species: Homo sapiens [TaxId:9606]
    Gene: USP28, KIAA1515
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96RU2
      • engineered mutation (445)
  • Chain 'C':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, AYE

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6h4hA (A:)
gpnpndwrrvdgwpvglknvgntcwfsaviqslfqlpefrrlvlsyslpqnvlencrsht
ekrnimfmqelqylfalmmgsnrkfvdpsaaldllkgafrsseeqqqdvsefthklldwl
edafqlavnvnsprnksenpmvqlfygtfltegvregkpfcnnetfgqyplqvngyrnld
eclegamvegdvellpsdhsvkygqerwftklppvltfelsrfefnqslgqpekihnkle
fpqiiymdrymyrskelirnkrecirklkeeikilqqkleryvkygsgparfplpdmlky
viefastkpasescppesdthmtlplssvhcsvsdqtskeststesssqdvestfssped
slpkskpltssrssmempsqpaprtvtdeeinfvktclqrwrseieqdiqdlktciastt
qtieqmycdpllrqvpyrlhavlvhdgqanaghywayiynqprqswlkyndisvtesswe
everdsygglrnvsayclmyindklpyfnaeaaptesdqmsevealsvelkhyiqednwr
feqeveeweeeqsckipqme

    Sequence, based on observed residues (ATOM records):
    >6h4hA (A:)
gpnpndwrrvdgwpvglknvgntcwfsaviqslfqlpefrrlvlsyslpqnvlencrsht
ekrnimfmqelqylfalmmgsnrkfvdpsaaldllkgafrsseeqqqdvsefthklldwl
edafqlavnvnsprnksenpmvqlfygtfltegvregkpfcnnetfgqyplqvngyrnld
eclegamvegdygqerwftklppvltfelsrfefnqslgqpekihnklefpqiiymdrym
yrskelirnkrecirklkeeikilqqkleryvkygsgparfplpdmlkyviefastkvtd
eeinfvktclqrwrseieqdiqdlktciasttqtieqmycdpllrqvpyrlhavlvhdgq
anaghywayiynqprqswlkyndisvtessweeverdsygglrnvsayclmyindklpyf
sdqmsevealsvelkhyiqednwrfeqeveeweeeqsc

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6h4hB (B:)
gpnpndwrrvdgwpvglknvgntcwfsaviqslfqlpefrrlvlsyslpqnvlencrsht
ekrnimfmqelqylfalmmgsnrkfvdpsaaldllkgafrsseeqqqdvsefthklldwl
edafqlavnvnsprnksenpmvqlfygtfltegvregkpfcnnetfgqyplqvngyrnld
eclegamvegdvellpsdhsvkygqerwftklppvltfelsrfefnqslgqpekihnkle
fpqiiymdrymyrskelirnkrecirklkeeikilqqkleryvkygsgparfplpdmlky
viefastkpasescppesdthmtlplssvhcsvsdqtskeststesssqdvestfssped
slpkskpltssrssmempsqpaprtvtdeeinfvktclqrwrseieqdiqdlktciastt
qtieqmycdpllrqvpyrlhavlvhdgqanaghywayiynqprqswlkyndisvtesswe
everdsygglrnvsayclmyindklpyfnaeaaptesdqmsevealsvelkhyiqednwr
feqeveeweeeqsckipqme

    Sequence, based on observed residues (ATOM records):
    >6h4hB (B:)
rvdgwpvglknvgntcwfsaviqslfqlpefrrlvlsysllencrshtekrnimfmqelq
ylfalmmgsnrkfvdpsaaldllkgaseeqqqdvsefthklldwledafqlavnvnenpm
vqlfygtfltegvregkpfcnnetfgqyplqvngyrnldeclegamvegqerwftklppv
ltfelsrfefnqslgqpekihnklefpqiiymdrymyrskelirnkrecirklkeeikil
qqkleryvkygsgparfplpdmlkyviefastdeeinfvktclqrwrseieqdiqdlktc
iasttqtieqmycdpllrqvpyrlhavlvhdgqanaghywayiynqprqswlkyndisvt
essweeverdsygglrnvsayclmyindklpevealsvelkhyiqednwrfeqeveewee

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6h4hC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrg

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6h4hD (D:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrg