PDB entry 6h47

View 6h47 on RCSB PDB site
Description: Human KRAS in complex with darpin K19
Class: signaling protein
Keywords: GTP-ASE, darpin, KRAS signalling, SIGNALING PROTEIN
Deposited on 2018-07-20, released 2019-04-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (3-168)
      • conflict (14)
    Domains in SCOPe 2.08: d6h47a_
  • Chain 'B':
    Compound: darpin K19
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H47
    Domains in SCOPe 2.08: d6h47b1, d6h47b2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6h47A (A:)
gshmteyklvvvgavgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldild
tagqeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnk
cdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkh

    Sequence, based on observed residues (ATOM records): (download) 
    >6h47A (A:)
mteyklvvvgavgvgksaltiqliqnhfvdedsyrkqvvidgetclldildtagqeeysa
mrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtvd
tkqaqdlarsygipfietsaktrqgvddafytlvreirkh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6h47B (B:)
mghhhhhhhhhhssghiegrhmdlgkklleaaragqddevrilmangadvnasdrwgwtp
lhlaawwghleivevllkrgadvsaadlhgqsplhlaamvghleivevllkygadvnakd
tmgatplhlaarsghleiveellkngadmnaqdkfgkttfdistdngnedlaeilqkl

    Sequence, based on observed residues (ATOM records): (download) 
    >6h47B (B:)
hmdlgkklleaaragqddevrilmangadvnasdrwgwtplhlaawwghleivevllkrg
advsaadlhgqsplhlaamvghleivevllkygadvnakdtmgatplhlaarsghleive
ellkngadmnaqdkfgktdlaeil