PDB entry 6h34

View 6h34 on RCSB PDB site
Description: The crystal structure of human carbonic anhydrase II in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide.
Class: lyase
Keywords: Protein-inhibitor binding, benzenesulfonamide, LYASE
Deposited on 2018-07-17, released 2018-12-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-12-19, with a file datestamp of 2018-12-14.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6h34a_
  • Heterogens: ZN, FKK, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6h34A (A:)
    mgmshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslr
    ilnnghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaael
    hlvhwntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnf
    dprgllpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepee
    lmvdnwrpaqplknrqikasfk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6h34A (A:)
    hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
    ghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvh
    wntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprg
    llpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvd
    nwrpaqplknrqikasf