PDB entry 6h2s

View 6h2s on RCSB PDB site
Description: Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/D181Q/A198L variant, pyruvate complex
Class: lyase
Keywords: aldolase, lyase
Deposited on 2018-07-16, released 2019-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-31, with a file datestamp of 2019-07-26.
Experiment type: XRAY
Resolution: 2.17 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-292)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2sa_
  • Chain 'B':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-292)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2sb_
  • Chain 'C':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-292)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2sc_
  • Chain 'D':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-292)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2sd_
  • Heterogens: PYR, GOL, PEG, IPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6h2sA (A:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6h2sB (B:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6h2sC (C:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6h2sD (D:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke