PDB entry 6h2r

View 6h2r on RCSB PDB site
Description: Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/D181Q/A198L variant
Class: lyase
Keywords: aldolase, lyase
Deposited on 2018-07-16, released 2019-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-31, with a file datestamp of 2019-07-26.
Experiment type: XRAY
Resolution: 1.57 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-292)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2ra_
  • Chain 'B':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-End)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2rb_
  • Chain 'C':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-292)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2rc_
  • Chain 'D':
    Compound: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54288 (0-292)
      • engineered mutation (155)
      • engineered mutation (179)
      • engineered mutation (196)
    Domains in SCOPe 2.08: d6h2rd_
  • Heterogens: IPA, GOL, EDO, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6h2rA (A:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6h2rB (B:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke

    Sequence, based on observed residues (ATOM records): (download) 
    >6h2rB (B:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilk

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6h2rC (C:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6h2rD (D:)
peiitpiitpftkdnridkeklkihaenlirkgidklfvngttglgpslspeeklenlka
vydvtnkiifqvgglnlddairlaklskdfdivgiasyapyyyprmsekhlvkyfktlce
vsphpvylynyptatgkdidakvakeigcftgvkdvieniihtldykrlnpnmlvysgsq
mliatvastgldgnvalgsnylpevtvtikklamerkidealklqflhdevieasrifgs
lssnyvltkyfqgydlgyprppifplddeeerqlikkvegiraklvelkilke