PDB entry 6h2q

View 6h2q on RCSB PDB site
Description: crystal structure of arg184gln mutant of human prolidase with mn ions and leupro ligand
Deposited on 2018-07-14, released 2018-08-15
The last revision was dated 2020-04-22, with a file datestamp of 2020-04-17.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Xaa-Pro Dipeptidase
    Species: Homo sapiens [TaxId:9606]
    Gene: PEPD, PRD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12955
      • engineered mutation (183)
  • Chain 'B':
    Compound: Xaa-Pro Dipeptidase
    Species: Homo sapiens [TaxId:9606]
    Gene: PEPD, PRD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12955
      • engineered mutation (183)
  • Heterogens: MN, GOL, LEU, PRO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6h2qA (A:)
maaatgpsfwlgnetlkvplalfalnrqrlcerlrknpavqagsivvlqggeetqryctd
tgvlfrqesffhwafgvtepgcygvidvdtgkstlfvprlpashatwmgkihskehfkek
yavddvqyvdeiasvltsqkpsvlltlrgvntdsgsvcreasfdgiskfevnntilhpei
vecqvfktdmelevlrytnkisseahrevmkavkvgmkeyeleslfehycysrggmrhss
ytcicgsgensavlhyghagapndrtiqngdmclfdmggeyycfasditcsfpangkfta
dqkavyeavlrssravmgamkpgvwwpdmhrladrihleelahmgilsgsvdamvqahlg
avfmphglghflgidvhdvggypegveridepglrslrtarhlqpgmvltvepgiyfidh
lldealadparasflnrevlqrfrgfggvrieedvvvtdsgielltcvprtveeieacma
gcdkaftpfsgpk

    Sequence, based on observed residues (ATOM records):
    >6h2qA (A:)
gpsfwlgnetlkvplalfalnrqrlcerlrknpavqagsivvlqggeetqryctdtgvlf
rqesffhwafgvtepgcygvidvdtgkstlfvprlpashatwmgkihskehfkekyavdd
vqyvdeiasvltsqkpsvlltlrgvntdsgsvcreasfdgiskfevnntilhpeivecqv
fktdmelevlrytnkisseahrevmkavkvgmkeyeleslfehycysrggmrhssytcic
gsgensavlhyghagapndrtiqngdmclfdmggeyycfasditcsfpangkftadqkav
yeavlrssravmgamkpgvwwpdmhrladrihleelahmgilsgsvdamvqahlgavfmp
hglghflgidvhdvggypegveridepglrslrtarhlqpgmvltvepgiyfidhlldea
ladparasflnrevlqrfrgfggvrieedvvvtdsgielltcvprtveeieacmagcftp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6h2qB (B:)
maaatgpsfwlgnetlkvplalfalnrqrlcerlrknpavqagsivvlqggeetqryctd
tgvlfrqesffhwafgvtepgcygvidvdtgkstlfvprlpashatwmgkihskehfkek
yavddvqyvdeiasvltsqkpsvlltlrgvntdsgsvcreasfdgiskfevnntilhpei
vecqvfktdmelevlrytnkisseahrevmkavkvgmkeyeleslfehycysrggmrhss
ytcicgsgensavlhyghagapndrtiqngdmclfdmggeyycfasditcsfpangkfta
dqkavyeavlrssravmgamkpgvwwpdmhrladrihleelahmgilsgsvdamvqahlg
avfmphglghflgidvhdvggypegveridepglrslrtarhlqpgmvltvepgiyfidh
lldealadparasflnrevlqrfrgfggvrieedvvvtdsgielltcvprtveeieacma
gcdkaftpfsgpk

    Sequence, based on observed residues (ATOM records):
    >6h2qB (B:)
gpsfwlgnetlkvplalfalnrqrlcerlrknpavqagsivvlqggeetqryctdtgvlf
rqesffhwafgvtepgcygvidvdtgkstlfvprlpashatwmgkihskehfkekyavdd
vqyvdeiasvltsqkpsvlltlrgvntdsgsvcreasfdgiskfevnntilhpeivecqv
fktdmelevlrytnkisseahrevmkavkvgmkeyeleslfehycysrggmrhssytcic
gsgensavlhyghagapndrtiqngdmclfdmggeyycfasditcsfpangkftadqkav
yeavlrssravmgamkpgvwwpdmhrladrihleelahmgilsgsvdamvqahlgavfmp
hglghflgidvhdvggypegveridepglrslrtarhlqpgmvltvepgiyfidhlldea
ladparasflnrevlqrfrgfggvrieedvvvtdsgielltcvprtveeieacmagcd