PDB entry 6h1v

View 6h1v on RCSB PDB site
Description: the crystal structure of pol2core in complex with dna and an incoming nucleotide, carrying an fe-s cluster
Deposited on 2018-07-12, released 2019-04-24
The last revision was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase epsilon catalytic subunit A
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: POL2, DUN2, YNL262W, N0825
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21951 (Start-1186)
      • engineered mutation (289)
      • engineered mutation (291)
  • Chain 'P':
    Compound: DNA (5'-d(p*tp*ap*ap*cp*cp*gp*cp*gp*tp*tp*(doc))-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'T':
    Compound: DNA (5'-d(p*ap*ap*tp*tp*gp*ap*ap*cp*gp*cp*gp*gp*tp*tp*a)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: SF4, DTP, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6h1vA (A:)
mmfgkkknnggsstarysagnkyntlsnnyalsaqqllnaskiddidsmmgferyvppqy
ngrfdakdidqipgrvgwltnmhatlvsqetlssgsngggnsndgervttnqgisgvdfy
fldeeggsfkstvvydpyffiacndesrvndveelvkkylesclkslqiirkedltmdnh
llglqktliklsfvnsnqlfearkllrpilqdnannnvqrniynvaangsekvdakhlie
direydvpyhvrvsidkdirvgkwykvtqqgfiedtrkiafadpvvmafaiattkpplkf
pdsavdqimmisymidgegflitnreiisediedfeytpkpeypgfftifnendevallq
rffehirdvrptvistfngdffdwpfihnrskihgldmfdeigfapdaegeykssycshm
dcfrwvkrdsylpqgsqglkavtqsklgynpieldpelmtpyafekpqhlseysvsdava
tyylymkyvhpfifslctiiplnpdetlrkgtgtlcemllmvqayqhnillpnkhtdpie
rfydghllesetyvgghvesleagvfrsdlknefkidpsaidellqelpealkfsveven
kssvdkvtnfeeiknqitqkllelkennirnelpliyhvdvasmypnimttnrlqpdsik
aerdcascdfnrpgktcarklkwawrgeffpskmdeynmikralqnetfpnknkfskkkv
ltfdelsyadqvihikkrlteysrkvyhrvkvseivereaivcqrenpfyvdtvksfrdr
ryefkglaktwkgnlskidpsdkhardeakkmivlydslqlahkvilnsfygyvmrkgsr
wysmemagitcltgatiiqmaralvervgrpleldtdgiwcilpksfpetyfftlengkk
lylsypcsmlnyrvhqkftnhqyqelkdplnyiyethsentiffevdgpykamilpsske
egkgikkryavfnedgslaelkgfelkrrgelqliknfqsdifkvflegdtlegcysava
svcnrwldvldshglmlededlvslicenrsmsktlkeyegqkstsittarrlgdflged
mvkdkglqckyiisskpfnapvteraipvaifsadipikrsflrrwtldpsledldirti
idwgyyrerlgsaiqkiitipaalqgvsnpvprvehpdwlkrkiatk

    Sequence, based on observed residues (ATOM records):
    >6h1vA (A:)
alsaqqllnaskiddidsmmgferyvppqyngrfdakdidqipgrvgwltnmhatlvsqe
nqgisgvdfyfldeeggsfkstvvydpyffiacndesrvndveelvkkylesclkslqii
rkedltmdnhllglqktliklsfvnsnqlfearkllrpilqdnannnvqrniynvdakhl
iedireydvpyhvrvsidkdirvgkwykvtqqgfiedtrkiafadpvvmafaiattkppl
kfpdsavdqimmisymidgegflitnreiisediedfeytpkpeypgfftifnendeval
lqrffehirdvrptvistfngdffdwpfihnrskihgldmfdeigfapdaegeykssycs
hmdcfrwvkrdsylpqgsqglkavtqsklgynpieldpelmtpyafekpqhlseysvsda
vatyylymkyvhpfifslctiiplnpdetlrkgtgtlcemllmvqayqhnillpnkhtdp
ierfydghllesetyvgghvesleagvfrsdlknefkidpsaidellqelpealkfsvev
enkssvdkvtnfeeiknqitqkllelkennirnelpliyhvdvasmypnimttnrlqpds
ikaerdcktcarklkwawrgeffpskmdeynmikralqnetfpnkkvltfdelsyadqvi
hikkrlteysrkvyhrvkvseivereaivcqrenpfyvdtvksfrdrryefkglaktwkg
nlskidpsdkhardeakkmivlydslqlahkvilnsfygyvmrkgsrwysmemagitclt
gatiiqmaralvervgrpleldtdgiwcilpksfpetyfftlengkklylsypcsmlnyr
vhqkftnhqyqelkdplnyiyethsentiffevdgpykamilpsskeegkgikkryavfn
edgslaelkgfelkrrgelqliknfqsdifkvflegdtlegcysavasvcnrwldvldsh
glmlededlvslicenrsmsktlkeyegqkstsittarrlgdflgedmvkdkglqckyii
sskpfnapvteraipvaifsadipikrsflrrwtldpsledldirtiidwgyyrerlgsa
iqkiitipaalqgvsnpvprvehpdwlkrkiatk

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.