PDB entry 6h1b

View 6h1b on RCSB PDB site
Description: structure of amide bond synthetase mcba k483a mutant from marinactinospora thermotolerans
Deposited on 2018-07-11, released 2018-09-05
The last revision was dated 2019-10-02, with a file datestamp of 2019-09-27.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fatty acid CoA ligase
    Species: Marinactinospora thermotolerans [TaxId:531310]
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4R1U5 (4-End)
      • expression tag (2-3)
      • engineered mutation (486)
  • Chain 'B':
    Compound: Fatty acid CoA ligase
    Species: Marinactinospora thermotolerans [TaxId:531310]
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4R1U5 (4-End)
      • expression tag (2-3)
      • engineered mutation (486)
  • Chain 'C':
    Compound: Fatty acid CoA ligase
    Species: Marinactinospora thermotolerans [TaxId:531310]
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4R1U5 (4-498)
      • expression tag (2-3)
      • engineered mutation (486)
  • Chain 'D':
    Compound: Fatty acid CoA ligase
    Species: Marinactinospora thermotolerans [TaxId:531310]
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4R1U5 (4-End)
      • expression tag (0-3)
      • engineered mutation (486)
  • Chain 'E':
    Compound: Fatty acid CoA ligase
    Species: Marinactinospora thermotolerans [TaxId:531310]
    Database cross-references and differences (RAF-indexed):
    • Uniprot R4R1U5 (4-498)
      • engineered mutation (486)
  • Heterogens: AMP, EQ2, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6h1bA (A:)
qgpamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhan
twraialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervs
vpvvlslgptsrgrdilaasvpegtplryrehpegiavvaftsgttgtpkgvahsstams
acvdaavsmygrgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaierer
athvflapnwlyqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygt
qeaafiaaltpddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsg
ywrdpertaqvlsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvlteh
pdvraaavvgvpdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsi
pvtpagapdkvkvrtwftd

    Sequence, based on observed residues (ATOM records):
    >6h1bA (A:)
pamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhantw
raialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervsvp
vvlslgptsrgrdilapegtplryrehpegiavvaftpkgvahsstamsacvdaavsmyg
rgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaiererathvflapnwl
yqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygtqeaafiaaltp
ddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsgywrdpertaqv
lsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvltehpdvraaavvgv
pdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsipvtpagapdkv
kvrtwft

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6h1bB (B:)
qgpamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhan
twraialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervs
vpvvlslgptsrgrdilaasvpegtplryrehpegiavvaftsgttgtpkgvahsstams
acvdaavsmygrgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaierer
athvflapnwlyqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygt
qeaafiaaltpddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsg
ywrdpertaqvlsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvlteh
pdvraaavvgvpdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsi
pvtpagapdkvkvrtwftd

    Sequence, based on observed residues (ATOM records):
    >6h1bB (B:)
pamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhantw
raialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervsvp
vvlslgptsrgrdilegtplryrehpegiavvaftgtpkgvahsstamsacvdaavsmyg
rgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaiererathvflapnwl
yqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygtqeaafiaaltp
ddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsgywrdpertaqv
lsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvltehpdvraaavvgv
pdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsipvagapdkvkv
rtwft

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6h1bC (C:)
qgpamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhan
twraialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervs
vpvvlslgptsrgrdilaasvpegtplryrehpegiavvaftsgttgtpkgvahsstams
acvdaavsmygrgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaierer
athvflapnwlyqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygt
qeaafiaaltpddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsg
ywrdpertaqvlsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvlteh
pdvraaavvgvpdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsi
pvtpagapdkvkvrtwftd

    Sequence, based on observed residues (ATOM records):
    >6h1bC (C:)
pamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhantw
raialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervsvp
vvlslgptsrgrdilaasvptplryrehpegiavvaftsgpkgvahsstamsacvdaavs
mygrpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaiererathvflapn
wlyqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygtqeaafiaal
tpddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsgywrdperta
qvlsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvltehpdvraaavv
gvpdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsipvtpagapd
kvkvrtwftd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6h1bD (D:)
qgpamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhan
twraialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervs
vpvvlslgptsrgrdilaasvpegtplryrehpegiavvaftsgttgtpkgvahsstams
acvdaavsmygrgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaierer
athvflapnwlyqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygt
qeaafiaaltpddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsg
ywrdpertaqvlsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvlteh
pdvraaavvgvpdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsi
pvtpagapdkvkvrtwftd

    Sequence, based on observed residues (ATOM records):
    >6h1bD (D:)
qgpamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhan
twraialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervs
vpvvlslgptsrgrdilatplryrehpegiavvafttpkgvahsstamsacvdaavsmyg
rgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaiererathvflapnwl
yqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygtqeaafiaaltp
ddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsgywrdpertaqv
lsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvltehpdvraaavvgv
pdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsipvtpagapdkv
kvrtwft

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6h1bE (E:)
qgpamgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhan
twraialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervs
vpvvlslgptsrgrdilaasvpegtplryrehpegiavvaftsgttgtpkgvahsstams
acvdaavsmygrgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaierer
athvflapnwlyqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygt
qeaafiaaltpddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsg
ywrdpertaqvlsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvlteh
pdvraaavvgvpdpdsgeavcaavvvadgadpdpehlralvrdhlgdlhvprrvefvrsi
pvtpagapdkvkvrtwftd

    Sequence, based on observed residues (ATOM records):
    >6h1bE (E:)
mgyarrvmdgigevavtgaggsvtgarlrhqvrllahalteagippgrgvaclhantwra
ialrlavqaigchyvglrptaavteqaraiaaadsaalvfepsvearaadllervsvpvv
lslgptsrgrdipegtplryrehpegiavvaftttgtpkgvahsstamsacvdaavsmyg
rgpwrflipiplsdlggelaqctlatggtvvlleefqpdavleaiererathvflapnwl
yqlaehpalprsdlsslrrvvyggapavpsrvaaarermgavlmqnygtqeaafiaaltp
ddharrelltavgrplphveveirddsggtlprgavgevwvrspmtmsgywrdpertaqv
lsggwlrtgdvgtfdedghlhltdrlqdiiiveaynvysrrvehvltehpdvraaavvgv
pdpdsgeavcaavvvadadpdpehlralvrdhlgdlhvprrvefvrsipvtpagapdkvk
vrtwftd