PDB entry 6h0t

View 6h0t on RCSB PDB site
Description: Crystal structure of native recombinant human bile salt activated lipase
Class: hydrolase
Keywords: Lipase, alpha-beta hydrolase., HYDROLASE
Deposited on 2018-07-10, released 2019-03-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-03-27, with a file datestamp of 2019-03-22.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bile salt-activated lipase
    Species: Homo sapiens [TaxId:9606]
    Gene: CEL, BAL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19835 (15-546)
      • expression tag (14)
      • engineered mutation (199)
      • engineered mutation (311)
    Domains in SCOPe 2.07: d6h0ta1, d6h0ta2
  • Heterogens: ZN, ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6h0tA (A:)
    hhhhhhhhenlyfqsklgavyteggfvegvnkklgllgdsvdifkgipfaaptkalenpq
    phpgwqgtlkaknfkkrclqatitqdstygdedclylniwvpqgrkqvsrdlpvmiwiyg
    gaflmgsghganflnnylydgeeiatrgnvivvtfnyrvgplgflstgdanlpgnyglrd
    qhmaiawvkrniaafggdpdnitlfgesaggasvslqtlspynkglirraisqsgvalsp
    wviqknplfwakkvaekvgcpvgdaarmaqclkvtdpraltlaykvplagleypmlhyvg
    fvpvidgdfipddpinlyanaadidyiagtnnmdghifasidmpainkgnkkvteedfyk
    lvseftitkglrgakttfdvyteswaqdpsqenkkktvvdfetdvlflvpteialaqhra
    naksaktyaylfshpsrmpvypkwvgadhaddiqyvfgkpfatptgyrpqdrtvskamia
    ywtnfaktgdpnmgdsavpthwepyttensgyleitkkmgsssmkrslrtnflrywtlty
    lalptvt
    

    Sequence, based on observed residues (ATOM records): (download)
    >6h0tA (A:)
    sklgavyteggfvegvnkklgllgdsvdifkgipfaaptkalenpqphpgwqgtlkaknf
    kkrclqatitqdstygdedclylniwvpqgrkqvsrdlpvmiwiyggaflylydgeeiat
    rgnvivvtfnyrvgplgflstgdanlpgnyglrdqhmaiawvkrniaafggdpdnitlfg
    esaggasvslqtlspynkglirraisqsgvalspwviqknplfwakkvaekvgcpvgdaa
    rmaqclkvtdpraltlaykypmlhyvgfvpvidgdfipddpinlyanaadidyiagtnnm
    dghifasidmpainkgnkkvteedfyklvseftitkglrgakttfdvyteswaqdpsqen
    kkktvvdfetdvlflvpteialaqhranaksaktyaylfshpsrmpvypkwvgadhaddi
    qyvfgkpfatptgyrpqdrtvskamiaywtnfaktgdpnmgdsavpthwepyttensgyl
    eitkkmgsssmkrslrtnflrywtltylalptvt