PDB entry 6h0m

View 6h0m on RCSB PDB site
Description: 17beta-hydroxysteroid dehydrogenase type 14 mutant k158a in complex with nicotinamide adenine dinucleotide
Deposited on 2018-07-10, released 2019-07-31
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 17-beta-hydroxysteroid dehydrogenase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: HSD17B14, DHRS10, SDR3, SDR47C1, UNQ502/PRO474
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BPX1
      • engineered mutation (157)
      • conflict (204)
  • Heterogens: NA, NAD, DMS, BGC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6h0mA (A:)
matgtryagkvvvvtgggrgigagivrafvnsgarvvicdkdesggraleqelpgavfil
cdvtqeddvktlvsetirrfgrldcvvnnaghhpppqrpeetsaqgfrqllelnllgtyt
ltklalpylrksqgnvinisslvgaigqaqavpyvatagavtamtkalaldespygvrvn
cispgniwtplweelaalmpdprasiregmlaqplgrmgqpaevgaaavflaseanfctg
iellvtggaelgygckasrstpvdapdips

    Sequence, based on observed residues (ATOM records):
    >6h0mA (A:)
tryagkvvvvtgggrgigagivrafvnsgarvvicdkdesggraleqelpgavfilcdvt
qeddvktlvsetirrfgrldcvvnnaghhpppqrpeetsaqgfrqllelnllgtytltkl
alpylrksqgnvinisslvgaigqaqavpyvatagavtamtkalaldespygvrvncisp
gniwtplweelaalmpdprasiregmlaqplgrmgqpaevgaaavflaseanfctgiell
vtggaelgygckaapdi