PDB entry 6h06

View 6h06 on RCSB PDB site
Description: fab cbtau-22.1 in complex with tau peptide v1088-5
Deposited on 2018-07-06, released 2018-07-25
The last revision was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 2.63 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: human fab antibody fragment of cbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Chain 'B':
    Compound: human fab antibody fragment of hcbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Chain 'C':
    Compound: human fab antibody fragment of cbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Chain 'D':
    Compound: human fab antibody fragment of hcbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Chain 'E':
    Compound: human fab antibody fragment of cbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Chain 'F':
    Compound: human fab antibody fragment of hcbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Chain 'G':
    Compound: microtubule-associated protein tau
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: human fab antibody fragment of cbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Chain 'I':
    Compound: microtubule-associated protein tau
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: microtubule-associated protein tau
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: microtubule-associated protein tau
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: human fab antibody fragment of hcbtau-22.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6H06 (0-End)
  • Heterogens: GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6h06A (A:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

    Sequence, based on observed residues (ATOM records):
    >6h06A (A:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapssksgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6h06B (B:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6h06B (B:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6h06C (C:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

    Sequence, based on observed residues (ATOM records):
    >6h06C (C:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapsskggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6h06D (D:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6h06D (D:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6h06E (E:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

    Sequence, based on observed residues (ATOM records):
    >6h06E (E:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6h06F (F:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6h06F (F:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6h06G (G:)
sprhlsnvsstgsidmvdspqlatla

    Sequence, based on observed residues (ATOM records):
    >6h06G (G:)
vdspqlat

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6h06H (H:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

    Sequence, based on observed residues (ATOM records):
    >6h06H (H:)
evqlvqsgaevkkpgapvkvscetsgyrfsdynvhwvrqapgqgpewigrispnsggtky
aqkfqgrvtmtrdmsmntaymelsglrsddtavyycvrghcdgttcsraywgqgtlvtvs
sastkgpsvfplapssgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6h06I (I:)
sprhlsnvsstgsidmvdspqlatla

    Sequence, based on observed residues (ATOM records):
    >6h06I (I:)
dmvdspqlat

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6h06J (J:)
sprhlsnvsstgsidmvdspqlatla

    Sequence, based on observed residues (ATOM records):
    >6h06J (J:)
vdspqla

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6h06K (K:)
sprhlsnvsstgsidmvdspqlatla

    Sequence, based on observed residues (ATOM records):
    >6h06K (K:)
vdspqla

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6h06L (L:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6h06L (L:)
dvvmtqsplslpvtpgepasiscrssqsllhrsghkylhwylqrpgqspqvliylgsnra
sgvpdrfsgsgsgtdftlkisrveaedvglyycmqtlqtpwtfgqgtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrge