PDB entry 6gzv

View 6gzv on RCSB PDB site
Description: identification of a druggable vp1-vp3 interprotomer pocket in the capsid of enteroviruses
Deposited on 2018-07-05, released 2019-06-05
The last revision was dated 2019-06-19, with a file datestamp of 2019-06-14.
Experiment type: EM
Resolution: 4 Å
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Capsid protein VP1
    Species: Coxsackievirus B3 (strain Nancy) [TaxId:103903]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: capsid protein VP2
    Species: Coxsackievirus B3 (strain Nancy) [TaxId:103903]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: capsid protein vp3
    Species: Coxsackievirus B3 (strain Nancy) [TaxId:103903]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: capsid protein VP4
    Species: Coxsackievirus B3 (strain Nancy) [TaxId:103903]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FHK

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gzvA (A:)
gpvedaitaaigrvadtvgtgptnseaipaltaaetghtsqvvpgdtmqtrhvknyhsrs
estienflcrsacvyfteyknsgakryaewvltprqaaqlrrklefftyvrfdleltfvi
tstqqpsttqnqdaqilthqimyvppggpvpdkvdsyvwqtstnpsvfwtegnapprmsi
pflsignaysnfydgwsefsrngvygintlnnmgtlyarhvnagstgpikstiriyfkpk
hvkawiprpprlcqyekaknvnfqpsgvtttrqsittmtntgaf

    Sequence, based on observed residues (ATOM records):
    >6gzvA (A:)
rvadtvgtgptnseaipaltaaetghtsqvvpgdtmqtrhvknyhsrsestienflcrsa
cvyfteyknsgakryaewvltprqaaqlrrklefftyvrfdleltfvitstqqpsttqnq
daqilthqimyvppggpvpdkvdsyvwqtstnpsvfwtegnapprmsipflsignaysnf
ydgwsefsrngvygintlnnmgtlyarhvnagstgpikstiriyfkpkhvkawiprpprl
cqyekaknvnfqpsgvtttrqsittmtnt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gzvB (B:)
sptveecgysdrarsitlgnstittqecanvvvgygvwpdylkdseataedqptqpdvat
crfytldsvqwqktspgwwwklpdalsnlglfgqnmqyhylgrtgytvhvqcnaskfhqg
cllvvcvpeaemgcatldntpssaellggdtakefadkpvasgsnklvqrvvynagmgvg
vgnltifphqwinlrtnnsativmpytnsvpmdnmfrhnnvtlmvipfvpldycpgstty
vpitvtiapmcaeynglrlaghq

    Sequence, based on observed residues (ATOM records):
    >6gzvB (B:)
gysdrarsitlgnstittqecanvvvgygvwpdylkdseataedqptqpdvatcrfytld
svqwqktspgwwwklpdalsnlglfgqnmqyhylgrtgytvhvqcnaskfhqgcllvvcv
peaemgcatldntpssaellggdtakefadkpvasgsnklvqrvvynagmgvgvgnltif
phqwinlrtnnsativmpytnsvpmdnmfrhnnvtlmvipfvpldycpgsttyvpitvti
apmcaeynglrlagh

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6gzvC (C:)
glptmntpgscqfltsddfqspsampqydvtpemripgevknlmeiaevdsvvpvqnvge
kvnsmeayqipvrsnegsgtqvfgfplqpgyssvfsrtllgeilnyythwsgsikltfmf
cgsamatgkfllaysppgagaptkrvdamlgthviwdvglqsscvlcipwisqthyrfva
sdeytaggfitcwyqtnivvpadaqsscyimcfvsacndfsvrllkdtpfisqqnffq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gzvD (D:)
mgaqvstqktgahetrlnasgnsiihytninyykdaasnsanrqdftqdpgkftepvkdi
mikslpaln

    Sequence, based on observed residues (ATOM records):
    >6gzvD (D:)
gaqvstqktgaihytninyykdaasnsanrqdftqdpgkftepvkdimikslpaln