PDB entry 6gyu

View 6gyu on RCSB PDB site
Description: cryo-em structure of the cbf3-msk complex of the budding yeast kinetochore
Deposited on 2018-07-02, released 2018-12-05
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Centromere DNA-binding protein complex CBF3 subunit C
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: CTF13, CBF3C, YMR094W, YM6543.01, YM9582.19
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Centromere DNA-binding protein complex CBF3 subunit B
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: CEP3, CBF3, CBF3B, CSL1, YMR168C, YM8520.17C
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Centromere DNA-binding protein complex CBF3 subunit B
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: CEP3, CBF3, CBF3B, CSL1, YMR168C, YM8520.17C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P40969 (4-563)
      • initiating methionine (0)
      • expression tag (1-3)
  • Chain 'D':
    Compound: Suppressor of kinetochore protein 1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: SKP1, CBF3D, YDR328C, D9798.14
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: centromere DNA-binding protein complex cbf3 subunit a
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: CBF2, CBF3A, CEP2, CTF14, NDC10, YGR140W
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gyuA (A:)
mpsfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpgkpsykrskrsk
kllrymypvfatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalew
tyldnelrlayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlv
dkclsileqkdlfatigevqfgqdeevgeekdvdvsgansdensspsstiknkkrsaskr
shsdngnvgathnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrdnpgkt
isyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpknfkslt
mkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldkseinq
itylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqvlvi

    Sequence, based on observed residues (ATOM records):
    >6gyuA (A:)
sfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpgrskrskkllrymy
pvfatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalewtyldnel
rlayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlvdkclsil
eqkdlfatigevqfgqdnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrd
npgktisyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpkn
fksltmkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldk
seinqitylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqv
lvi

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gyuB (B:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevssllqhaaylqdlpnvdvyreenstevlywkiisldrdldqyln
ksskpplktldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyli
yydtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesa
avkqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfki
lqndikiielkndemfslikglgslvplnklrqeslleeedenntepsdfrtiveefqse
ynisdils

    Sequence, based on observed residues (ATOM records):
    >6gyuB (B:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevsslnvdvyreenstevlywkiisldrdldqylnksskpplktld
airreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyliyydtadsllkv
ihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesaavkqllvdlte
ltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfkilqndikiielk
ndemfslikglgslvplnsdfrtiveefqseynisdils

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gyuC (C:)
mfnritassskeylpdlllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmn
ylqkdqsfqlmnfamenlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliw
svftmciyympveklaeifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcd
fmahpdirlvqaylilatttfpydepllanslltqcihtfknfhvddfrpllnddpvesi
akvtlgrifyrlcgcdylqsgprkpialhtevssllqhaaylqdlpnvdvyreenstevl
ywkiisldrdldqylnksskpplktldairreldifqykvdsleedfrsnnsrfqkfial
fqistvswklfkmyliyydtadsllkvihyskviislivnnfhakseffnrhpmvmqtit
rvvsfisfyqifvesaavkqllvdlteltanlptifgskldklvylterlsklkllwdkv
qlldsgdsfyhpvfkilqndikiielkndemfslikglgslvplnklrqeslleeedenn
tepsdfrtiveefqseynisdils

    Sequence, based on observed residues (ATOM records):
    >6gyuC (C:)
mfnritassskeylpdlllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmn
ylqkdqsfqlmnfamenlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliw
svftmciyympveklaeifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcd
fmahpdirlvqaylilatttfpydepllanslltqcihtfknfhvddfrpllnddpvesi
akvtlgrifyrlcgcdylqsgprkpialhtevssllnstevlywkiisldrdldqylnks
skpplktldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyliyy
dtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesaav
kqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfkilq
ndikiielkndemfslikglgslvplnsdfrtiveefqseynisdils

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gyuD (D:)
mvtsnvvlvsgegerftvdkkiaerslllknylndmhdsnlqnnsdsesdsdsetnhksk
dnnngddddedddeivmpvpnvrssvlqkviewaehhrdsnfpdeddddsrksapvdswd
reflkvdqemlyeiilaanylnikplldagckvvaemirgrspeeirrtfnivndftpee
eaairrenewaedr

    Sequence, based on observed residues (ATOM records):
    >6gyuD (D:)
snvvlvsgegerftvdkkiaerslllknylndeivmpvpnvrssvlqkviewaehhrdsn
fpdeddddsrksapvdswdreflkvdqemlyeiilaanylnikplldagckvvaemirgr
speeirrtfnivndftpeeeaairrenewae

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6gyuE (E:)
mrssilfllklmkimdvqqqqeamssedrfqelvdslkprtahqyktyytkyiqwcqlnq
iiptpednsvnsvpykdlpisaelihwflldtlitddkpgekreetedldeeeensfkia
tlkkiigslnflsklckvhenpnanidtkylesvtklhthwidsqkaittnetnntntqv
lcppllkvslnlwnpetnhlsekffktcseklrflvdfqlrsylnlsfeerskirfgslk
lgkrdrdaiiyhkvthsaekkdtpghhqllallpqdcpficpqttlaaylylrfygipsv
skgdgfpnlnadengsllqdipilrgkslttypreetfsnyyttvfrychlpykrreyfn
kcnlvyptwdedtfrtffneenhgnwleqpeafafpdkipfdfkkimnfkspytsystna
kkdpfpppkdllvqifpeideykrhdyeglsqnsrdfldlmevlrerflsnlpwiykffp
nhdifqdpifgnsdfqsyfndktihskgspilsfdilpgfnkiyknktnfysllierpsq
ltfasshnpdthptqkqesegplqmsqldttqlnellkqqsfeyvqfqtlsnfqillsvf
nkifeklemkkssrgyilhqlnlfkitlderikkskiddadkfirdnqpikkeenivned
gpntsrrtkrpkqirllsiadssdesstedsnvfkkdgesiedgaygenedendsemqeq
lksminelinskistflrdqmdqfelkinalldkileekvtriieqklgshtgkfstlkr
pqlymteehnvgfdmevpkklrtsgkyaetvkdnddhqamsttaspspeqdqeaksytde
qefmldksidsiegiilewftpnakyanqcvhsmnksgnkswrancealykerksivefy
iylvnhesldrykavdiceklrdqnegsfsrlakflrkwrhdhqnsfdgllvylsn

    Sequence, based on observed residues (ATOM records):
    >6gyuE (E:)
edrfqelvdslkprtahqyktyytkyiqwcqlnqiiptpednsvnsvpykdlpisaelih
wflldtlitddkpgekreetedldeeeensfkiatlkkiigslnflsklckvhenpnani
dtkylesvtklhthwidsqkaittnetnntntqvlcppllkvslnlwnpetnhlsekffk
tcseklrflvdfqlrsylnlsfeerskirfgslklgkrdrdaiiyhkvthsaekkdtpgh
hqllallpqdcpficpqttlaaylylrfygipsvskgdgfpnlnadengsllqdipilrg
kslttypreetfsnyyttvfrychlpykrreyfnkcnlvyptwdedtfrtffneenhgnw
leqpeafafpdkipfdfkkimnfkspytsystnakkdpfpppkdllvqifpeideykrhd
yeglsqnsrdfldlmevlrerflsnlpwiykffpnhdifqdpifgnsdfqsyfndktihs
kgspilsfdilpgfnkiyknktnfysllierp