PDB entry 6gys

View 6gys on RCSB PDB site
Description: cryo-em structure of the cbf3-cen3 complex of the budding yeast kinetochore
Deposited on 2018-07-01, released 2018-12-05
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: EM
Resolution: 4.4 Å
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Centromere DNA-binding protein complex CBF3 subunit C
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CTF13, CBF3C, YMR094W, YM6543.01, YM9582.19
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Centromere DNA-binding protein complex CBF3 subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CEP3, CBF3, CBF3B, CSL1, YMR168C, YM8520.17C
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Centromere DNA-binding protein complex CBF3 subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CEP3, CBF3, CBF3B, CSL1, YMR168C, YM8520.17C
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Suppressor of kinetochore protein 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SKP1, CBF3D, YDR328C, D9798.14
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: centromere DNA-binding protein complex cbf3 subunit a
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CBF2, CBF3A, CEP2, CTF14, NDC10, YGR140W
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: DNA (52-mer)
    Species: Saccharomyces cerevisiae [TaxId:4932]
  • Chain 'G':
    Compound: DNA (52-mer)
    Species: Saccharomyces cerevisiae [TaxId:4932]
  • Chain 'H':
    Compound: Centromere DNA-binding protein complex CBF3 subunit C
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CTF13, CBF3C, YMR094W, YM6543.01, YM9582.19
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Centromere DNA-binding protein complex CBF3 subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CEP3, CBF3, CBF3B, CSL1, YMR168C, YM8520.17C
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Centromere DNA-binding protein complex CBF3 subunit B
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CEP3, CBF3, CBF3B, CSL1, YMR168C, YM8520.17C
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: Suppressor of kinetochore protein 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: SKP1, CBF3D, YDR328C, D9798.14
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: centromere DNA-binding protein complex cbf3 subunit a
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CBF2, CBF3A, CEP2, CTF14, NDC10, YGR140W
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gysA (A:)
mpsfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpgkpsykrskrsk
kllrymypvfatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalew
tyldnelrlayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlv
dkclsileqkdlfatigevqfgqdeevgeekdvdvsgansdensspsstiknkkrsaskr
shsdngnvgathnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrdnpgkt
isyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpknfkslt
mkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldkseinq
itylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqvlvi

    Sequence, based on observed residues (ATOM records):
    >6gysA (A:)
sfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpskrskkllrymypv
fatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalewtyldnelrl
ayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlvdkclsileq
kdlfatigevqfgqdnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrdnp
gktisyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpknfk
sltmkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldkse
inqitylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqvlv
i

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gysB (B:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevssllqhaaylqdlpnvdvyreenstevlywkiisldrdldqyln
ksskpplktldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyli
yydtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesa
avkqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfki
lqndikiielkndemfslikglgslvplnklrqeslleeedenntepsdfrtiveefqse
ynisdils

    Sequence, based on observed residues (ATOM records):
    >6gysB (B:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevsslnvdvyreenstevlywkiisldrdldqylnksskpplktld
airreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyliyydtadsllkv
ihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesaavkqllvdlte
ltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfkilqndikiielk
ndemfslikglgslvplnsdfrtiveefqseynisdils

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gysC (C:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevssllqhaaylqdlpnvdvyreenstevlywkiisldrdldqyln
ksskpplktldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyli
yydtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesa
avkqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfki
lqndikiielkndemfslikglgslvplnklrqeslleeedenntepsdfrtiveefqse
ynisdils

    Sequence, based on observed residues (ATOM records):
    >6gysC (C:)
tqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstitassskeylpdlllfwqn
yeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfamenlgalyf
gsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympveklaeifsvyp
lheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylilatttfpy
depllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcdylqsgpr
kpialhtevssllqhaaylqdnstevlywkiisldrdldqylnksskpplktldairrel
difqykvdsleedfrsnnsrfqkfialfqistvswklfkmyliyydtadsllkvihyskv
iislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesaavkqllvdlteltanlp
tifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfkilqndikiielkndemfs
likglgslvplnsdfrtiveefqseynisdils

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gysD (D:)
mvtsnvvlvsgegerftvdkkiaerslllknylndmhdsnlqnnsdsesdsdsetnhksk
dnnngddddedddeivmpvpnvrssvlqkviewaehhrdsnfpdeddddsrksapvdswd
reflkvdqemlyeiilaanylnikplldagckvvaemirgrspeeirrtfnivndftpee
eaairrenewaedr

    Sequence, based on observed residues (ATOM records):
    >6gysD (D:)
snvvlvsgegerftvdkkiaerslllknylndeivmpvpnvrssvlqkviewaehhrdsn
fpdeddddsrksapvdswdreflkvdqemlyeiilaanylnikplldagckvvaemirgr
speeirrtfnivndftpeeeaairrenewae

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6gysE (E:)
mrssilfllklmkimdvqqqqeamssedrfqelvdslkprtahqyktyytkyiqwcqlnq
iiptpednsvnsvpykdlpisaelihwflldtlitddkpgekreetedldeeeensfkia
tlkkiigslnflsklckvhenpnanidtkylesvtklhthwidsqkaittnetnntntqv
lcppllkvslnlwnpetnhlsekffktcseklrflvdfqlrsylnlsfeerskirfgslk
lgkrdrdaiiyhkvthsaekkdtpghhqllallpqdcpficpqttlaaylylrfygipsv
skgdgfpnlnadengsllqdipilrgkslttypreetfsnyyttvfrychlpykrreyfn
kcnlvyptwdedtfrtffneenhgnwleqpeafafpdkipfdfkkimnfkspytsystna
kkdpfpppkdllvqifpeideykrhdyeglsqnsrdfldlmevlrerflsnlpwiykffp
nhdifqdpifgnsdfqsyfndktihskgspilsfdilpgfnkiyknktnfysllierpsq
ltfasshnpdthptqkqesegplqmsqldttqlnellkqqsfeyvqfqtlsnfqillsvf
nkifeklemkkssrgyilhqlnlfkitlderikkskiddadkfirdnqpikkeenivned
gpntsrrtkrpkqirllsiadssdesstedsnvfkkdgesiedgaygenedendsemqeq
lksminelinskistflrdqmdqfelkinalldkileekvtriieqklgshtgkfstlkr
pqlymteehnvgfdmevpkklrtsgkyaetvkdnddhqamsttaspspeqdqeaksytde
qefmldksidsiegiilewftpnakyanqcvhsmnksgnkswrancealykerksivefy
iylvnhesldrykavdiceklrdqnegsfsrlakflrkwrhdhqnsfdgllvylsn

    Sequence, based on observed residues (ATOM records):
    >6gysE (E:)
edrfqelvdslkprtahqyktyytkyiqwcqlnqiiptnsvpykdlpisaelihwflldt
litddkpgekreetedldeeeensfkiatlkkiigslnflsklckvhenpnanidtkyle
svtklhthwidsqkaittnetnntntqvlcppllkvslnlwnpetnhlsekffktcsekl
rflvdfqlrsylnlsfeerskirfgslklgkrdrdaiiyhkvthsaekkdtpghhqllal
lpqdcpficpqttlaaylylrfygipsvskgdgfpnlnadengsllqdipilrgksltty
preetfsnyyttvfrychlpykrreyfnkcnlvyptwdedtfrtffneenhgnwleqpea
fafpdkipfdfkkimnfkspytsystnakkdpfpppkdllvqifpeideykrhdyeglsq
nsrdfldlmevlrerflsnlpwiykffpnhdifqdpifgnsdfqsyfndktihskgspil
sfdilpgfnkiyknktnfysllierp

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6gysH (H:)
mpsfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpgkpsykrskrsk
kllrymypvfatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalew
tyldnelrlayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlv
dkclsileqkdlfatigevqfgqdeevgeekdvdvsgansdensspsstiknkkrsaskr
shsdngnvgathnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrdnpgkt
isyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpknfkslt
mkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldkseinq
itylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqvlvi

    Sequence, based on observed residues (ATOM records):
    >6gysH (H:)
sfnpvrflelpidirkevyfhldgnfcgahpypidilyksndvelpskrskkllrymypv
fatylnifeyspqliekwleyafwlrydclvldcfkvnhlydgtlidalewtyldnelrl
ayfnkasmlevwytfkeykkwvidsvafdeldllnvsniqfnidnltpqlvdkclsileq
kdlfatigevqfgqdnqltsisvirtirsmesmkslrkitvrgeklyellinfhgfrdnp
gktisyivkrrineirlsrmnqisrtgladftrwdnlqklvlsrvayidlnsivfpknfk
sltmkrvskikwwnieenilkelkvdkrtfkslyikeddskftkffnlrhtrikeldkse
inqitylrcqaivwlsfrtlnhiklqnvsevfnniivpralfdskrveiyrcekisqvlv
i

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6gysI (I:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevssllqhaaylqdlpnvdvyreenstevlywkiisldrdldqyln
ksskpplktldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyli
yydtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesa
avkqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfki
lqndikiielkndemfslikglgslvplnklrqeslleeedenntepsdfrtiveefqse
ynisdils

    Sequence, based on observed residues (ATOM records):
    >6gysI (I:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevsslnvdvyreenstevlywkiisldrdldqylnksskpplktld
airreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyliyydtadsllkv
ihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesaavkqllvdlte
ltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfkilqndikiielk
ndemfslikglgslvplnsdfrtiveefqseynisdils

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6gysJ (J:)
mfnrttqlkskhpcsvctrrkvkcdrmipcgncrkrgqdsecmkstklitassskeylpd
lllfwqnyeywitniglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfame
nlgalyfgsigdiselylrveqywdrradknhsvdgkywdaliwsvftmciyympvekla
eifsvyplheylgsnkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylil
atttfpydepllanslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcd
ylqsgprkpialhtevssllqhaaylqdlpnvdvyreenstevlywkiisldrdldqyln
ksskpplktldairreldifqykvdsleedfrsnnsrfqkfialfqistvswklfkmyli
yydtadsllkvihyskviislivnnfhakseffnrhpmvmqtitrvvsfisfyqifvesa
avkqllvdlteltanlptifgskldklvylterlsklkllwdkvqlldsgdsfyhpvfki
lqndikiielkndemfslikglgslvplnklrqeslleeedenntepsdfrtiveefqse
ynisdils

    Sequence, based on observed residues (ATOM records):
    >6gysJ (J:)
hpcsvctrrkvkcdrmipcgncrkrgqdsecmkstitassskeylpdlllfwqnyeywit
niglyktkqrdltrtpanldtdteecmfwmnylqkdqsfqlmnfamenlgalyfgsigdi
selylrveqywdrradknhsvdgkywdaliwsvftmciyympveklaeifsvyplheylg
snkrlnwedgmqlvmcqnfarcslfqlkqcdfmahpdirlvqaylilatttfpydeplla
nslltqcihtfknfhvddfrpllnddpvesiakvtlgrifyrlcgcdylqsgprkpialh
tenstevlywkiisldrdldqylnksskpplktldairreldifqykvdsleedfrsnns
rfqkfialfqistvswklfkmyliyydtadsllkvihyskviislivnnfhakseffnrh
pmvmqtitrvvsfisfyqifvesaavkqllvdlteltanlptifgskldklvylterlsk
lkllwdkvqlldsgdsfyhpvfkilqndikiielkndemfslikglgslvplnsdfrtiv
eefqseynisdils

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6gysK (K:)
mvtsnvvlvsgegerftvdkkiaerslllknylndmhdsnlqnnsdsesdsdsetnhksk
dnnngddddedddeivmpvpnvrssvlqkviewaehhrdsnfpdeddddsrksapvdswd
reflkvdqemlyeiilaanylnikplldagckvvaemirgrspeeirrtfnivndftpee
eaairrenewaedr

    Sequence, based on observed residues (ATOM records):
    >6gysK (K:)
snvvlvsgegerftvdkkiaerslllknylndeivmpvpnvrssvlqkviewaehhrdsn
fpdeddddsrksapvdswdreflkvdqemlyeiilaanylnikplldagckvvaemirgr
speeirrtfnivndftpeeeaairrenewae

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6gysL (L:)
mrssilfllklmkimdvqqqqeamssedrfqelvdslkprtahqyktyytkyiqwcqlnq
iiptpednsvnsvpykdlpisaelihwflldtlitddkpgekreetedldeeeensfkia
tlkkiigslnflsklckvhenpnanidtkylesvtklhthwidsqkaittnetnntntqv
lcppllkvslnlwnpetnhlsekffktcseklrflvdfqlrsylnlsfeerskirfgslk
lgkrdrdaiiyhkvthsaekkdtpghhqllallpqdcpficpqttlaaylylrfygipsv
skgdgfpnlnadengsllqdipilrgkslttypreetfsnyyttvfrychlpykrreyfn
kcnlvyptwdedtfrtffneenhgnwleqpeafafpdkipfdfkkimnfkspytsystna
kkdpfpppkdllvqifpeideykrhdyeglsqnsrdfldlmevlrerflsnlpwiykffp
nhdifqdpifgnsdfqsyfndktihskgspilsfdilpgfnkiyknktnfysllierpsq
ltfasshnpdthptqkqesegplqmsqldttqlnellkqqsfeyvqfqtlsnfqillsvf
nkifeklemkkssrgyilhqlnlfkitlderikkskiddadkfirdnqpikkeenivned
gpntsrrtkrpkqirllsiadssdesstedsnvfkkdgesiedgaygenedendsemqeq
lksminelinskistflrdqmdqfelkinalldkileekvtriieqklgshtgkfstlkr
pqlymteehnvgfdmevpkklrtsgkyaetvkdnddhqamsttaspspeqdqeaksytde
qefmldksidsiegiilewftpnakyanqcvhsmnksgnkswrancealykerksivefy
iylvnhesldrykavdiceklrdqnegsfsrlakflrkwrhdhqnsfdgllvylsn

    Sequence, based on observed residues (ATOM records):
    >6gysL (L:)
edrfqelvdslkprtahqyktyytkyiqwcqlnqiiptnsvpykdlpisaelihwflldt
litddkpgekreetedldeeeensfkiatlkkiigslnflsklckvhenpnanidtkyle
svtklhthwidsqkaittnetnntntqvlcppllkvslnlwnpetnhlsekffktcsekl
rflvdfqlrsylnlsfeerskirfgslklgkrdrdaiiyhkvthsaekkdtpghhqllal
lpqdcpficpqttlaaylylrfygipsvskgdgfpnlnadengsllqdipilrgksltty
preetfsnyyttvfrychlpykrreyfnkcnlvyptwdedtfrtffneenhgnwleqpea
fafpdkipfdfkkimnfkspytsystnakkdpfpppkdllvqifpeideykrhdyeglsq
nsrdfldlmevlrerflsnlpwiykffpnhdifqdpifgnsdfqsyfndktihskgspil
sfdilpgfnkiyknktnfysllierp