PDB entry 6gyr

View 6gyr on RCSB PDB site
Description: transcription factor dimerization activates the p300 acetyltransferase
Deposited on 2018-07-01, released 2018-10-17
The last revision was dated 2018-11-14, with a file datestamp of 2018-11-09.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone acetyltransferase p300
    Species: Homo sapiens [TaxId:9606]
    Gene: EP300, P300
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q09472 (1-587)
      • expression tag (0)
      • engineered mutation (422)
  • Chain 'B':
    Compound: Histone acetyltransferase p300
    Species: Homo sapiens [TaxId:9606]
    Gene: EP300, P300
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q09472 (1-587)
      • expression tag (0)
      • engineered mutation (422)
  • Chain 'C':
    Compound: Histone acetyltransferase p300
    Species: Homo sapiens [TaxId:9606]
    Gene: EP300, P300
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q09472 (1-587)
      • engineered mutation (422)
  • Chain 'D':
    Compound: Histone acetyltransferase p300
    Species: Homo sapiens [TaxId:9606]
    Gene: EP300, P300
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q09472 (1-587)
      • expression tag (0)
      • engineered mutation (422)
  • Heterogens: ZN, 01K

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6gyrA (A:)
akkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivkspmdlstikr
kldtgqyqepwqyvddiwlmfnnawlynrktsrvykycsklsevfeqeidpvmqslgycc
grklefspqtlccygkqlctiprdatyysyqnryhfcekcfneiqgesvslgddpsqpqt
tinkeqfskrkndtldpelfvectecgrkmhqicvlhheiiwpagfvcdgclkksartrk
enkfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfv
dsgemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhff
rpkclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlq
ewfkkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqee
eerkreentgnkkkpgmpnvsndlsqklyatmekhkevffvirliagpaanslppivdpd
plipcdlmdgrdafltlardkhlefsslrraqwstmcmlvelhtqsqd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gyrB (B:)
akkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivkspmdlstikr
kldtgqyqepwqyvddiwlmfnnawlynrktsrvykycsklsevfeqeidpvmqslgycc
grklefspqtlccygkqlctiprdatyysyqnryhfcekcfneiqgesvslgddpsqpqt
tinkeqfskrkndtldpelfvectecgrkmhqicvlhheiiwpagfvcdgclkksartrk
enkfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfv
dsgemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhff
rpkclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlq
ewfkkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqee
eerkreentgnkkkpgmpnvsndlsqklyatmekhkevffvirliagpaanslppivdpd
plipcdlmdgrdafltlardkhlefsslrraqwstmcmlvelhtqsqd

    Sequence, based on observed residues (ATOM records):
    >6gyrB (B:)
akkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivkspmdlstikr
kldtgqyqepwqyvddiwlmfnnawlynrktsrvykycsklsevfeqeidpvmqslgycc
grklefspqtlccygkqlctiprdatyysyqnryhfcekcfneiqgesvslgddpsqpqt
tinkeqfskrkndtldpelfvectecgrkmhqicvlhheiiwpagfvcdgclkksartrk
enkfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfv
dsgemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhff
rpkclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlq
ewfkkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqee
eerkreentpgmpnvsndlsqklyatmekhkevffvirliagpaanslppivdpdplipc
dlmdgrdafltlardkhlefsslrraqwstmcmlvelhtqsqd

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gyrC (C:)
akkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivkspmdlstikr
kldtgqyqepwqyvddiwlmfnnawlynrktsrvykycsklsevfeqeidpvmqslgycc
grklefspqtlccygkqlctiprdatyysyqnryhfcekcfneiqgesvslgddpsqpqt
tinkeqfskrkndtldpelfvectecgrkmhqicvlhheiiwpagfvcdgclkksartrk
enkfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfv
dsgemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhff
rpkclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlq
ewfkkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqee
eerkreentgnkkkpgmpnvsndlsqklyatmekhkevffvirliagpaanslppivdpd
plipcdlmdgrdafltlardkhlefsslrraqwstmcmlvelhtqsqd

    Sequence, based on observed residues (ATOM records):
    >6gyrC (C:)
kkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivkspmdlstikrk
ldtgqyqepwqyvddiwlmfnnawlynrktsrvykycsklsevfeqeidpvmqslgyccg
rklefspqtlccygkqlctiprdatyysyqnryhfcekcfneiqgesvslgddpsqpqtt
inkeqfskrkndtldpelfvectecgrkmhqicvlhheiiwpagfvcdgclkksartrke
nkfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfvd
sgemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhffr
pkclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlqe
wfkkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqeee
erkreentndlsqklyatmekhkevffvirliagpaanslppivdpdplipcdlmdgrda
fltlardkhlefsslrraqwstmcmlvelhtqsqd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gyrD (D:)
akkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivkspmdlstikr
kldtgqyqepwqyvddiwlmfnnawlynrktsrvykycsklsevfeqeidpvmqslgycc
grklefspqtlccygkqlctiprdatyysyqnryhfcekcfneiqgesvslgddpsqpqt
tinkeqfskrkndtldpelfvectecgrkmhqicvlhheiiwpagfvcdgclkksartrk
enkfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfv
dsgemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhff
rpkclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlq
ewfkkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqee
eerkreentgnkkkpgmpnvsndlsqklyatmekhkevffvirliagpaanslppivdpd
plipcdlmdgrdafltlardkhlefsslrraqwstmcmlvelhtqsqd

    Sequence, based on observed residues (ATOM records):
    >6gyrD (D:)
akkifkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivkspmdlstikr
kldtgqyqepwqyvddiwlmfnnawlynrktsrvykycsklsevfeqeidpvmqslgycc
grklefspqtlccygkqlctiprdatyysyqnryhfcekcfneiqgesvslgddpsqpqt
tinkeqfskrkndtldpelfvectecgrkmhqicvlhheiiwpagfvcdgclkksartrk
enkfsakrlpstrlgtflenrvndflrrqnhpesgevtvrvvhasdktvevkpgmkarfv
dsgemaesfpyrtkalfafeeidgvdlcffgmhvqeygsdcpppnqrrvyisyldsvhff
rpkclrtavyheiligyleyvkklgyttghiwacppsegddyifhchppdqkipkpkrlq
ewfkkmldkavserivhdykdifkqatedrltsakelpyfegdfwpnvleesikeleqee
eerkreentkpgmpnvsndlsqklyatmekhkevffvirliagpaanslppivdpdplip
cdlmdgrdafltlardkhlefsslrraqwstmcmlvelhtqsqd