PDB entry 6gyj

View 6gyj on RCSB PDB site
Description: Mouse thymidylate synthase crystal soaked in phenolphthalein
Class: transferase
Keywords: fragment screening, fragment, inhibitor, TRANSFERASE
Deposited on 2018-06-30, released 2019-08-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Mus musculus [TaxId:10090]
    Gene: Tyms
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6gyja_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Mus musculus [TaxId:10090]
    Gene: Tyms
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6gyjb_
  • Heterogens: FGT, SO4, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6gyjA (A:)
mlvvgselqsdaqqlsaeaprhgelqylrqvehilrcgfkkedrtgtgtlsvfgmqarys
lrdefpllttkrvfwkgvleellwfikgstnakelsskgvriwdangsrdfldslgfsar
qegdlgpvygfqwrhfgaeykdmdsdysgqgvdqlqkvidtiktnpddrriimcawnpkd
lplmalppchalcqfyvvngelscqlyqrsgdmglgvpfniasyalltymiahitglqpg
dfvhtlgdahiylnhieplkiqlqreprpfpklkilrkvetiddfkvedfqiegynphpt
ikmemav

    Sequence, based on observed residues (ATOM records): (download) 
    >6gyjA (A:)
rhgelqylrqvehilrcgfkkedrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvle
ellwfikgstnakelsskgvriwdangsrdfldslgfsarqegdlgpvygfqwrhfgaey
kdmdsdysgqgvdqlqkvidtiktnpddrriimcawnpkdlplmalppchalcqfyvvng
elscqlyqrsgdmglgvpfniasyalltymiahitglqpgdfvhtlgdahiylnhieplk
iqlqreprpfpklkilrkvetiddfkvedfqiegynphpt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6gyjB (B:)
mlvvgselqsdaqqlsaeaprhgelqylrqvehilrcgfkkedrtgtgtlsvfgmqarys
lrdefpllttkrvfwkgvleellwfikgstnakelsskgvriwdangsrdfldslgfsar
qegdlgpvygfqwrhfgaeykdmdsdysgqgvdqlqkvidtiktnpddrriimcawnpkd
lplmalppchalcqfyvvngelscqlyqrsgdmglgvpfniasyalltymiahitglqpg
dfvhtlgdahiylnhieplkiqlqreprpfpklkilrkvetiddfkvedfqiegynphpt
ikmemav

    Sequence, based on observed residues (ATOM records): (download) 
    >6gyjB (B:)
hgelqylrqvehilrcgfkkedrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvlee
llwfikgstnakelsskgvriwdangsrdfldslgfsarqegdlgpvygfqwrhfgaeyk
dmdsdysgqgvdqlqkvidtiktnpddrriimcawnpkdlplmalppchalcqfyvvnge
lscqlyqrsgdmglgvpfniasyalltymiahitglqpgdfvhtlgdahiylnhieplki
qlqreprpfpklkilrkvetiddfkvedfqiegynphp