PDB entry 6gx8

View 6gx8 on RCSB PDB site
Description: Alpha-galactosidase from Thermotoga maritima in complex with hydrolysed cyclohexene-based carbasugar mimic of galactose
Class: hydrolase
Keywords: glycoside hydrolase, galactosidase, carbohydrate processing enzyme, inhibitor, HYDROLASE
Deposited on 2018-06-26, released 2018-08-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-08-22, with a file datestamp of 2018-08-17.
Experiment type: XRAY
Resolution: 1.42 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-galactosidase
    Species: THERMOTOGA MARITIMA MSB8 [TaxId:243274]
    Gene: galA, TM_1192, Tmari_1199
    Database cross-references and differences (RAF-indexed):
    • Uniprot G4FEF4 (23-End)
      • expression tag (14-22)
    Domains in SCOPe 2.08: d6gx8a1, d6gx8a2, d6gx8a3
  • Heterogens: FH2, SO4, MG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6gx8A (A:)
    mgsshhhhhhssglvprgshmasmeifgktfregrfvlkeknftvefavekihlgwkisg
    rvkgspgrlevlrtkapekvlvnnwqswgpcrvvdafsfkppeidpnwrytasvvpdvle
    rnlqsdyfvaeegkvygflsskiahpffavedgelvayleyfdvefddfvpleplvvled
    pntplllekyaelvgmennarvpkhtptgwcswyhyfldltweetlknlklaknfpfevf
    qiddayekdigdwlvtrgdfpsveemakviaengfipgiwtapfsvsetsdvfnehpdwv
    vkengepkmayrnwnkkiyaldlskdevlnwlfdlfsslrkmgyryfkidflfagavpge
    rkknitpiqafrkgietirkavgedsfilgcgspllpavgcvdgmrigpdtapfwgehie
    dngapaarwalrnaitryfmhdrfwlndpdclilreektdltqkekelysytcgvldnmi
    iesddlslvrdhgkkvlketlellggrprvqnimsedlryeivssgtlsgnvkivvdlns
    reyhlekegksslkkrvvkredgrnfyfyeegere
    

    Sequence, based on observed residues (ATOM records): (download)
    >6gx8A (A:)
    vprgshmasmeifgktfregrfvlkeknftvefavekihlgwkisgrvkgspgrlevlrt
    kapekvlvnnwqswgpcrvvdafsfkppeidpnwrytasvvpdvlernlqsdyfvaeegk
    vygflsskiahpffavedgelvayleyfdvefddfvpleplvvledpntplllekyaelv
    gmennarvpkhtptgwcswyhyfldltweetlknlklaknfpfevfqiddayekdigdwl
    vtrgdfpsveemakviaengfipgiwtapfsvsetsdvfnehpdwvvkengepkmayrnw
    nkkiyaldlskdevlnwlfdlfsslrkmgyryfkidflfagavpgerkknitpiqafrkg
    ietirkavgedsfilgcgspllpavgcvdgmrigpdtapfwgehiedngapaarwalrna
    itryfmhdrfwlndpdclilreektdltqkekelysytcgvldnmiiesddlslvrdhgk
    kvlketlellggrprvqnimsedlryeivssgtlsgnvkivvdlnsreyhleke