PDB entry 6gx0

View 6gx0 on RCSB PDB site
Description: Blood group synthase AAGlyB in complex with UDP-Gal and cryoprotected with PEG 3350
Class: transferase
Keywords: blood group synthase, glycosyltransferase, dual specificity, cis-AB mutant, transferase
Deposited on 2018-06-26, released 2019-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-10, with a file datestamp of 2019-07-05.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase)
    Species: Homo sapiens [TaxId:9606]
    Gene: ABO
    Database cross-references and differences (RAF-indexed):
    • Uniprot F0X360 (7-End)
      • expression tag (1-6)
      • engineered mutation (209)
    Domains in SCOPe 2.08: d6gx0a1, d6gx0a2
  • Heterogens: MN, GDU, SO4, PEG, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6gx0A (A:)
maigefmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqntti
gltvfaikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevr
aykrwqdvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgf
ygssreaftyerrpqsqayipkdegdfyyggaffggsvqevqrltrachqammvdqangi
eavwhdeshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavpknhqavrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >6gx0A (A:)
aigefmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttig
ltvfaikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevra
ykrwqdvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgfy
gssreaftyerrpqsqayipkdegdfyyggaffggsvqevqrltrachqammvdqangie
avwhdeshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavp