SCOPe 2.08: Structural Classification of Proteins

PDB entry 6gvs

View 6gvs on RCSB PDB site
Description: engineered glycolyl-coa reductase comprising 8 mutations with bound nadp+
Deposited on 2018-06-21, released 2018-11-28
The last revision was dated 2018-12-19, with a file datestamp of 2018-12-14.
Experiment type: XRAY
Resolution: 2.58 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'B':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'C':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'D':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'E':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'F':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'G':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'H':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'I':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Chain 'J':
Compound: aldehyde dehydrogenase
Species: Rhodopseudomonas palustris BisB18 [TaxId:316056]
Gene: RPC_1174
Database cross-references and differences (RAF-indexed):
- Uniprot Q21A49 (Start-521)
  - engineered mutation (221)
  - engineered mutation (256)
  - engineered mutation (260)
  - engineered mutation (279)
  - engineered mutation (325-326)
  - engineered mutation (328)
  - engineered mutation (480)
Heterogens: NAP, K, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>6gvsA (A:)
mahhhhhhvgtndaniadvvtkvlgeygapgavsvaaltakspdgksnssadadvvarmv
akairdhagtaqpsgnaatssaavsdgvfetmdaaveaaalaqqqyllcsmsdrarfvqg
irdvilnqdtlekmsrmaveetgmgnyehkliknrlagektpgiedlttdafsgdngltl
veyspfgvigaitpttnptetivcnsigmlaagnsvvfsphgrarqvslllvrlinqkla
algapenlvvtvekpsrentlammahpkvrmlvatggpalvkavlstgkkaigagagnpp
vvvdetaniekaacdivngcsfdnnitctaekeiiavaqiadylifnlkkngayeikdpa
vlqqlqdlvltakggpqtkcvgksavwllsqigisvdasikiilmevprehpfvqeelmm
pilplvrvetvddaidlaievehdnrhtaimhstdvrkltkmakliqttifvkngpsyag
hgaggegystftiagptgegltsaksfarrrkcvmvealnir