PDB entry 6gvn

View 6gvn on RCSB PDB site
Description: tubulin:tm-3 darpin complex
Deposited on 2018-06-21, released 2019-04-24
The last revision was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha chain
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0VWZ0 (0-End)
      • conflict (231)
      • conflict (339)
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0VWY9 (0-End)
      • conflict (200)
      • conflict (315)
  • Chain 'F':
    Compound: tm-3 darpin
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GVN
  • Heterogens: GTP, MG, SO4, MES, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gvnA (A:)
    mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
    hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
    rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
    vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
    slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
    qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpp
    tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
    aredmaalekdyeevgvdsvegegeeegeey
    

    Sequence, based on observed residues (ATOM records):
    >6gvnA (A:)
    mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktgddsfntffsetgagkhvp
    ravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrir
    kladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavve
    pynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssitaslr
    fdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmv
    kcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpptvv
    pggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefseare
    dmaalekdyeevgv
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gvnB (B:)
    mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
    prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
    rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
    epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
    rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdsknmm
    aacdprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
    lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
    eyqqyqdatadeqgefeeeegedea
    

    Sequence, based on observed residues (ATOM records):
    >6gvnB (B:)
    mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
    prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
    rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
    epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
    rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdsknmm
    aacdprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
    lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
    eyqqyqdatad
    

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6gvnF (F:)
    mrgshhhhhhgsdlgkklleaaragqddevrilmangadvnatdasgltplhlaatyghl
    eivevllkhgadvnaidimgstplhlaalighleivevllkhgadvnavdtwgdtplrla
    aimghleivevllkhgadvnaqdkfgktafdtsidngsedlaeilqkln
    

    Sequence, based on observed residues (ATOM records):
    >6gvnF (F:)
    dlgkklleaaragqddevrilmangadvnatdasgltplhlaatyghleivevllkhgad
    vnaidimgstplhlaalighleivevllkhgadvnavdtwgdtplrlaaimghleivevl
    lkhgadvn