PDB entry 6gu6
View 6gu6 on RCSB PDB site
Description: CDK1/Cks2 in complex with Dinaciclib
Class: cell cycle
Keywords: cdk1, cks2, inhibitor, cell cycle
Deposited on
2018-06-19, released
2018-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-01-30, with a file datestamp of
2019-01-25.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cyclin-dependent kinase 1
Species: Homo sapiens [TaxId:9606]
Gene: CDK1, CDC2, CDC28A, CDKN1, P34CDC2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6gu6a_ - Chain 'B':
Compound: Cyclin-dependent kinases regulatory subunit 2
Species: Homo sapiens [TaxId:9606]
Gene: CKS2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6gu6b_ - Heterogens: 1QK, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6gu6A (A:)
gplgsmedytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisll
kelrhpnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqg
ivfchsrrvlhrdlkpqnlliddkgtikladfglarafgipirvythevvtlwyrspevl
lgsarystpvdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslq
dykntfpkwkpgslashvknldengldllskmliydpakrisgkmalnhpyfndldnqik
km
Sequence, based on observed residues (ATOM records): (download)
>6gu6A (A:)
medytkiekigegtygvvykgrhkttgqvvamkkirleseeegvpstaireisllkelrh
pnivslqdvlmqdsrlylifeflsmdlkkyldsippgqymdsslvksylyqilqgivfch
srrvlhrdlkpqnlliddkgtikladfglarafgipithevvtlwyrspevllgsaryst
pvdiwsigtifaelatkkplfhgdseidqlfrifralgtpnnevwpeveslqdykntfpk
wkpgslashvknldengldllskmliydpakrisgkmalnhpyfndld
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6gu6B (B:)
gplgsmahkqiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwv
hymihepephillfrrplpkdqqk
Sequence, based on observed residues (ATOM records): (download)
>6gu6B (B:)
qiyysdkyfdehyeyrhvmlprelskqvpkthlmseeewrrlgvqqslgwvhymihepep
hillfrrplp