PDB entry 6gtc

View 6gtc on RCSB PDB site
Description: transition state structure of cpf1(cas12a) i1 conformation
Deposited on 2018-06-18, released 2018-12-19
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: EM
Resolution: 3.91 Å
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: CRISPR-associated endonuclease Cas12a
    Species: Francisella tularensis subsp. novicida U112 [TaxId:401614]
    Gene: cas12a, cpf1, FTN_1397
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0Q7Q2 (0-End)
      • conflict (1005)
  • Chain 'B':
    Compound: RNA (28-mer)
    Species: Francisella tularensis subsp. novicida U112, synthetic [TaxId:401614]
  • Chain 'C':
    Compound: DNA (5'-d(p*tp*gp*ap*cp*tp*tp*cp*tp*cp*tp*ap*ap*cp*ap*ap*gp*cp*tp*cp*g)-3')
    Species: Francisella tularensis subsp. novicida U112, synthetic [TaxId:401614]
  • Chain 'D':
    Compound: DNA (5'-d(p*cp*gp*ap*gp*cp*tp*cp*gp*tp*tp*ap*gp*ap*gp*ap*ap*g)-3')
    Species: Francisella tularensis subsp. novicida U112, synthetic [TaxId:401614]

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gtcA (A:)
msiyqefvnkyslsktlrfelipqgktlenikarglilddekrakdykkakqiidkyhqf
fieeilssvcisedllqnysdvyfklkksdddnlqkdfksakdtikkqiseyikdsekfk
nlfnqnlidakkgqesdlilwlkqskdngielfkansditdidealeiiksfkgwttyfk
gfhenrknvyssndiptsiiyrivddnlpkflenkakyeslkdkapeainyeqikkdlae
eltfdidyktsevnqrvfsldevfeianfnnylnqsgitkfntiiggkfvngentkrkgi
neyinlysqqindktlkkykmsvlfkqilsdtesksfvidkleddsdvvttmqsfyeqia
afktveeksiketlsllfddlkaqkldlskiyfkndksltdlsqqvfddysvigtavley
itqqiapknldnpskkeqeliakktekakylsletiklaleefnkhrdidkqcrfeeila
nfaaipmifdeiaqnkdnlaqisikyqnqgkkdllqasaeddvkaikdlldqtnnllhkl
kifhisqsedkanildkdehfylvfeecyfelanivplynkirnyitqkpysdekfklnf
enstlangwdknkepdntailfikddkyylgvmnkknnkifddkaikenkgegykkivyk
llpgankmlpkvffsaksikfynpsedilrirnhsthtkngspqkgyekfefniedcrkf
idfykqsiskhpewkdfgfrfsdtqrynsidefyrevenqgykltfenisesyidsvvnq
gklylfqiynkdfsayskgrpnlhtlywkalfdernlqdvvyklngeaelfyrkqsipkk
ithpakeaianknkdnpkkesvfeydlikdkrftedkfffhcpitinfkssgankfndei
nlllkekandvhilsidrgerhlayytlvdgkgniikqdtfniigndrmktnyhdklaai
ekdrdsarkdwkkinnikemkegylsqvvheiaklvieynaivvfqdlnfgfkrgrfkve
kqvyqklekmlieklnylvfkdnefdktggvlrayqltapfetfkkmgkqtgiiyyvpag
ftskicpvtgfvnqlypkyesvsksqeffskfdkicynldkgyfefsfdyknfgdkaakg
kwtiasfgsrlinfrnsdknhnwdtrevyptkelekllkdysieyghgecikaaicgesd
kkffakltsvlntilqmrnsktgteldylispvadvngnffdsrqapknmpqdadangay
higlkglmllgriknnqegkklnlvikneeyfefvqnrnngsefelenlyfqgelrrqas
alehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6gtcA (A:)
msiyqefvnkyslsktlrfelipqgktlenikarglilddekrakdykkakqiidkyhqf
fieeilssvcisedllqnysdvyfklkksdddnlqkdfksakdtikkqiseyikdsekfk
nlfnqnlidakkgqesdlilwlkqskdngielfkansditdidealeiiksfkgwttyfk
gfhenrknvyssndiptsiiyrivddnlpkflenkakyeslkdkapeainyeqikkdlae
eltfdidyktsevnqrvfsldevfeianfnnylnqsgitkfntiiggkfvngentkrkgi
neyinlysqqindktlkkykmsvlfkqilsdtdkleddsdvvttmqsfyeqiaafktvee
ksiketlsllfddlkaqkldlskiyfkndksltdlsqqvfddysvigtavleyitqqiap
knqeliakktekakylsletiklaleefnkhrdidkqcrfeeilanfaaipmifdeiaqn
kdnlaqisikyqnqgkkdllqasaeddvkaikdlldqtnnllhklkifhisqsedkanil
dkdehfylvfeecyfelanivplynkirnyitqkpysdekfklnfenstlangwdknkep
dntailfikddkyylgvmnkknnkifddkaikenkgegykkivykllpgankmlpkvffs
aksikfynpsedilrirnhsthtkngspqkgyekfefniedcrkfidfykqsiskhpewk
dfgfrfsdtqrynsidefyrevenqgykltfenisesyidsvvnqgklylfqiynkdfsa
yskgrpnlhtlywkalfdernlqdvvyklngeaelfyrkqsipkkithpakeaianknkd
npkkesvfeydlikdkrftedkfffhcpitinfkssgankfndeinlllkekandvhils
idrgerhlayytlvdgkgniikqdtfniigndrmktnyhdklaaiekdrdsarkdwkkin
nikemkegylsqvvheiaklvieynaivvfqdlnfgfkrgrfkvekqvyqklekmliekl
nylvfkdnefdktggvlrayqltapfetfkkmgkqtgiiyyvpagftskicpvtgfvnql
ypkyesvsksqeffskfdkicynldkgyfefsfdyknfgdkaakgkwtiasfgsrlinfr
nsnwdtrevyptkelekllkdysieyghgecikaaicgesdkkffakltsvlntilqmrn
sktgteldylispvadvngnffdsrqapknmpqdadangayhiglkglmllgriknnqeg
kklnlvikneeyfefvqnrn

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.