PDB entry 6gt3

View 6gt3 on RCSB PDB site
Description: crystal structure of the a2a-star2-bril562 in complex with azd4635 at 2.0a resolution
Deposited on 2018-06-15, released 2019-06-26
The last revision was dated 2020-07-08, with a file datestamp of 2020-07-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a
    Species: Homo sapiens [TaxId:9606]
    Gene: ADORA2A, ADORA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29274 (10-216)
      • expression tag (7-9)
      • engineered mutation (62)
      • engineered mutation (96)
      • engineered mutation (115)
      • engineered mutation (130)
      • engineered mutation (162)
      • engineered mutation (210)
    • Uniprot P0ABE7 (217-321)
      • engineered mutation (223)
      • engineered mutation (318)
      • linker (322)
    • Uniprot P29274 (323-End)
      • engineered mutation (339)
      • engineered mutation (343)
      • engineered mutation (381)
  • Heterogens: F9Q, NA, CLR, OLA, OLC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gt3A (A:)
dykddddgappimgssvyitvelaiavlailgnvlvcwavwlnsnlqnvtnyfvvslaaa
dilvgvlaipfaitistgfcaachgclfiacfvlvlaqssifsllaiaidryiaiaiplr
ynglvtgtraagiiaicwvlsfaigltpmlgwnncgqpkegkahsqgcgegqvaclfedv
vpmnymvyfnffacvlvplllmlgvylrifaaarrqladlednwetlndnlkviekadna
aqvkdaltkmraaaldaqkatppkledkspdspemkdfrhgfdilvgqiddalklanegk
vkeaqaaaeqlkttrnayiqkylerarstlqkevhaaksaaiiaglfalcwlplhiincf
tffcpdcshaplwlmylaivlahtnsvvnpfiyayrirefrqtfrkiirshvlrqqepfk
aaahhhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6gt3A (A:)
gappimgssvyitvelaiavlailgnvlvcwavwlnsnlqnvtnyfvvslaaadilvgvl
aipfaitistgfcaachgclfiacfvlvlaqssifsllaiaidryiaiaiplrynglvtg
traagiiaicwvlsfaigltpmlgwnncgqpkegkahsqgcgegqvaclfedvvpmnymv
yfnffacvlvplllmlgvylrifaaarrqladlednwetlndnlkviekadnaaqvkdal
tkmraaaldaqkmkdfrhgfdilvgqiddalklanegkvkeaqaaaeqlkttrnayiqky
lerarstlqkevhaaksaaiiaglfalcwlplhiincftffcpdcshaplwlmylaivla
htnsvvnpfiyayrirefrqtfrkiirs