PDB entry 6gqx

View 6gqx on RCSB PDB site
Description: kras-169 q61h gppnhp + ch-2
Class: oncoprotein
Keywords: kras, oncoprotein
Deposited on 2018-06-08, released 2019-02-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-20, with a file datestamp of 2019-02-15.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
      • engineered mutation (64)
    Domains in SCOPe 2.08: d6gqxa1, d6gqxa2
  • Chain 'B':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (3-169)
      • expression tag (0-2)
      • engineered mutation (63)
    Domains in SCOPe 2.08: d6gqxb1, d6gqxb2
  • Chain 'C':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d6gqxc1, d6gqxc2
  • Chain 'D':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (1-3)
    Domains in SCOPe 2.08: d6gqxd1, d6gqxd2
  • Chain 'E':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (1-3)
    Domains in SCOPe 2.08: d6gqxe1, d6gqxe2
  • Chain 'F':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d6gqxf1, d6gqxf2
  • Heterogens: MG, GNP, F8K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6gqxA (A:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6gqxB (B:)
fqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldild
tagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnk
cdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqxB (B:)
fqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldild
tagheesamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkc
dlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6gqxC (C:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqxC (C:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagsamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6gqxD (D:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqxD (D:)
fqgmteyklvvvgaggvgksaltiqliqnhfvdedsyrkqvvidgetclldildtagmrd
qymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtvdtkq
aqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6gqxE (E:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqxE (E:)
fqgmteyklvvvgaggvgksaltiqliqnhfvdedsyrkqvvidgetclldildtasamr
dqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtvdtk
qaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6gqxF (F:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqxF (F:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdedsyrkqvvidgetclldildtagsa
mrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtvd
tkqaqdlarsygipfietsaktrqgvddafytlvreirkhk