PDB entry 6gqw

View 6gqw on RCSB PDB site
Description: kras-169 q61h gppnhp + ch-1
Class: oncoprotein
Keywords: kras, oncoprotein
Deposited on 2018-06-08, released 2019-02-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-02, with a file datestamp of 2019-09-27.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (1-3)
      • engineered mutation (64)
    Domains in SCOPe 2.08: d6gqwa1, d6gqwa2
  • Chain 'B':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
      • engineered mutation (64)
    Domains in SCOPe 2.08: d6gqwb1, d6gqwb2
  • Chain 'C':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d6gqwc1, d6gqwc2
  • Chain 'D':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d6gqwd1, d6gqwd2
  • Chain 'E':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
      • conflict (23)
    Domains in SCOPe 2.08: d6gqwe1, d6gqwe2
  • Chain 'F':
    Compound: GTPase KRas
    Species: Homo sapiens [TaxId:9606]
    Gene: KRAS, KRAS2, RASK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01116 (4-170)
      • expression tag (0-3)
    Domains in SCOPe 2.08: d6gqwf1, d6gqwf2
  • Heterogens: MG, GNP, F8T, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6gqwA (A:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqwA (A:)
fqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldild
tagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnk
cdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6gqwB (B:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqwB (B:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtaghesamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkc
dlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6gqwC (C:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqwC (C:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagsamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6gqwD (D:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqwD (D:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydedsyrkqvvidgetclldildta
grdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtvd
tkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6gqwE (E:)
yfqgmteyklvvvgaggvgksalviqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqwE (E:)
yfqgmteyklvvvgaggvgksalviqliqnhfvdeydpedsyrkqvvidgetclldildt
agrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtv
dtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6gqwF (F:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldil
dtagheeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgn
kcdlpsrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqwF (F:)
yfqgmteyklvvvgaggvgksaltiqliqnhfvdeydptedsyrkqvvidgetclldild
tagamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlps
rtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk