PDB entry 6gqs

View 6gqs on RCSB PDB site
Description: Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) variant K112R in complex with AMPCP
Class: chaperone
Keywords: CHAPERONE, Hsp90, NTD, alpha, K112R, complex, nucleotide, AMPCP
Deposited on 2018-06-08, released 2018-10-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-10-10, with a file datestamp of 2018-10-05.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: HSP90AA1, HSP90A, HSPC1, HSPCA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07900 (20-End)
      • expression tag (14-19)
      • engineered mutation (131)
    Domains in SCOPe 2.08: d6gqsa1, d6gqsa2
  • Heterogens: A12, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6gqsA (A:)
mgsshhhhhhssglvprgshmpeetqtqdqpmeeeevetfafqaeiaqlmsliintfysn
keiflrelisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtk
adlinnlgtiarsgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqy
awessaggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitl
fvekerdkevsddeae

    Sequence, based on observed residues (ATOM records): (download) 
    >6gqsA (A:)
vprgshmpeetqtqdqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssd
aldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiarsg
tkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrt
dtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerd