PDB entry 6gpx

View 6gpx on RCSB PDB site
Description: crystal structure of ccr2a in complex with mk-0812
Deposited on 2018-06-07, released 2019-01-02
The last revision was dated 2019-03-13, with a file datestamp of 2019-03-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: C-C chemokine receptor type 2,Rubredoxin,C-C chemokine receptor type 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CCR2, CMKBR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41597 (Start-200)
      • conflict (41)
      • conflict (146)
    • Uniprot P00268 (200-202)
    • Uniprot P41597 (202-292)
      • conflict (263)
      • expression tag (344)
      • conflict (212)
      • expression tag (293-297)
  • Chain 'B':
    Compound: C-C chemokine receptor type 2,Rubredoxin,C-C chemokine receptor type 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CCR2, CMKBR2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41597 (Start-200)
      • conflict (41)
      • conflict (146)
    • Uniprot P00268 (200-End)
    • Uniprot P41597
      • conflict (314)
      • conflict (263)
  • Heterogens: ZN, OLA, F7N, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gpxA (A:)
    gapchkfdvkqigaqllpplyslvfifgfvgnmlvvlilinykklkcltdiyllnlaisd
    llflitlplwahsaanewvfgnamcklftglyhigyfggiffiilltidrylaivhavfa
    lkartvtfgvvtsvitwlvavfasvpniiftkcqkedsvyvcgpyfprgwnnfhtimrni
    lglvlpllimvicysgilktllrmkkytctvcgyiynpedgdpdngvnpgtdfkdipddw
    vcplcgvgkdqfeeveeekkrhrdvrviftimivyflfwtpynivillntfqeffglsnc
    estsqldqatqvtetlgmthccinpiiyafvgekfrslfhialgevlfq
    

    Sequence, based on observed residues (ATOM records):
    >6gpxA (A:)
    dvkqigaqllpplyslvfifgfvgnmlvvlilinykklkcltdiyllnlaisdllflitl
    plwahsaanewvfgnamcklftglyhigyfggiffiilltidrylaivhtvtfgvvtsvi
    twlvavfasvpniiftkcqkedsvyvcgpyfprgwnnfhtimrnilglvlpllimvicys
    gilktllrmkkytctvcgyiynpedgdpdngvnpgtdfkdipddwvcplcgvgkdqfeev
    erdvrviftimivyflfwtpynivillntfqeffglsncestsqldqatqvtetlgmthc
    cinpiiyafvgekfrslfhialge
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gpxB (B:)
    gapchkfdvkqigaqllpplyslvfifgfvgnmlvvlilinykklkcltdiyllnlaisd
    llflitlplwahsaanewvfgnamcklftglyhigyfggiffiilltidrylaivhavfa
    lkartvtfgvvtsvitwlvavfasvpniiftkcqkedsvyvcgpyfprgwnnfhtimrni
    lglvlpllimvicysgilktllrmkkytctvcgyiynpedgdpdngvnpgtdfkdipddw
    vcplcgvgkdqfeeveeekkrhrdvrviftimivyflfwtpynivillntfqeffglsnc
    estsqldqatqvtetlgmthccinpiiyafvgekfrslfhialgevlfq
    

    Sequence, based on observed residues (ATOM records):
    >6gpxB (B:)
    fdvkqigaqllpplyslvfifgfvgnmlvvlilinykklkcltdiyllnlaisdllflit
    lplwahsaanewvfgnamcklftglyhigyfggiffiilltidrylaivhavfalkartv
    tfgvvtsvitwlvavfasvpniiftkcqkedsvyvcgpyfprgwnnfhtimrnilglvlp
    llimvicysgilktldvrviftimivyflfwtpynivillntfqeffglsncestsqldq
    atqvtetlgmthccinpiiyafv