PDB entry 6gou

View 6gou on RCSB PDB site
Description: development of alkyl glycerone phosphate synthase inhibitors: complex with inhibitor 2i
Deposited on 2018-06-04, released 2019-01-02
The last revision was dated 2019-01-02, with a file datestamp of 2018-12-28.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alkyldihydroxyacetonephosphate synthase, peroxisomal
    Species: Cavia porcellus [TaxId:10141]
    Gene: AGPS
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: alkyldihydroxyacetonephosphate synthase, peroxisomal
    Species: Cavia porcellus [TaxId:10141]
    Gene: AGPS
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: alkyldihydroxyacetonephosphate synthase, peroxisomal
    Species: Cavia porcellus [TaxId:10141]
    Gene: AGPS
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: alkyldihydroxyacetonephosphate synthase, peroxisomal
    Species: Cavia porcellus [TaxId:10141]
    Gene: AGPS
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD, F6T

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gouA (A:)
maeaaaaaaaaaaagetsassgsaaerdpdqdragrrlrvlsghllgrpqealstnecka
rraasaataaptatpaapesgiipkkrqelmkwngwgyndskfflnkkgqleltgkrypl
sgvalptfkdwiqntfginldhkttskaslnpsdtppsivnedflhelkktnisysqead
drvfrahghclheifllregmferipdivlwptchddvvkivnlackynlciipigggts
vsyglmcpadetrtiisldtsqmnrilwvdennltahveagitgqelerqlkesgyctgh
epdslefstvggwistrasgmkkniygniedlvvhmkvvtprgviekscqgprmstgpdi
hhfimgsegtlgviteatikirptpeyqkygsvafpnfeqgvaclreiakqrcapasirl
mdnqqfqfghalkpqvssiftsfldglkkfyitkfkgfdpnqlsvatllfegdrekvlqh
ekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyiigesfetsapwdrvvdl
crnvkerirreckekgvqfpplstcrvtqtydagaciyfyfafnyrgisdplavfeqtea
aareeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkdyvdptnifgnrnll

    Sequence, based on observed residues (ATOM records):
    >6gouA (A:)
giipkkrqelmkwngwgyndskfflnkkgqleltgkryplsgvalptfkdwiqntfginl
dhkttskaslnpsdtppsivnedflhelkktnisysqeaddrvfrahghclheifllreg
mferipdivlwptchddvvkivnlackynlciipigggtsvsyglmcpadetrtiisldt
sqmnrilwvdennltahveagitgqelerqlkesgyctghepdslefstvggwistrasg
mkkniygniedlvvhmkvvtprgviekscqgprmstgpdihhfimgsegtlgviteatik
irptpeyqkygsvafpnfeqgvaclreiakqrcapasirlmdnqqfqfghalkpdpnqls
vatllfegdrekvlqhekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyii
gesfetsapwdrvvdlcrnvkerirreckekgvqfpplstcrvtqtydagaciyfyfafn
yrgisdplavfeqteaaareeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkd
yvdptnifgnrnll

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gouB (B:)
maeaaaaaaaaaaagetsassgsaaerdpdqdragrrlrvlsghllgrpqealstnecka
rraasaataaptatpaapesgiipkkrqelmkwngwgyndskfflnkkgqleltgkrypl
sgvalptfkdwiqntfginldhkttskaslnpsdtppsivnedflhelkktnisysqead
drvfrahghclheifllregmferipdivlwptchddvvkivnlackynlciipigggts
vsyglmcpadetrtiisldtsqmnrilwvdennltahveagitgqelerqlkesgyctgh
epdslefstvggwistrasgmkkniygniedlvvhmkvvtprgviekscqgprmstgpdi
hhfimgsegtlgviteatikirptpeyqkygsvafpnfeqgvaclreiakqrcapasirl
mdnqqfqfghalkpqvssiftsfldglkkfyitkfkgfdpnqlsvatllfegdrekvlqh
ekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyiigesfetsapwdrvvdl
crnvkerirreckekgvqfpplstcrvtqtydagaciyfyfafnyrgisdplavfeqtea
aareeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkdyvdptnifgnrnll

    Sequence, based on observed residues (ATOM records):
    >6gouB (B:)
giipkkrqelmkwngwgyndskfflnkkgqleltgkryplsgvalptfkdwiqntfginl
tppsivnedflhelkktnisysqeaddrvfrahghclheifllregmferipdivlwptc
hddvvkivnlackynlciipigggtsvsyglmcpadetrtiisldtsqmnrilwvdennl
tahveagitgqelerqlkesgyctghepdslefstvggwistrasgmkkniygniedlvv
hmkvvtprgviekscqgprmstgpdihhfimgsegtlgviteatikirptpeyqkygsva
fpnfeqgvaclreiakqrcapasirlmdnqqfqfghalkpdpnqlsvatllfegdrekvl
qhekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyiigesfetsapwdrvv
dlcrnvkerirreckekgvqfpplstcrvtqtydagaciyfyfafnyrgisdplavfeqt
eaaareeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkdyvdptnifgnrnll

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gouC (C:)
maeaaaaaaaaaaagetsassgsaaerdpdqdragrrlrvlsghllgrpqealstnecka
rraasaataaptatpaapesgiipkkrqelmkwngwgyndskfflnkkgqleltgkrypl
sgvalptfkdwiqntfginldhkttskaslnpsdtppsivnedflhelkktnisysqead
drvfrahghclheifllregmferipdivlwptchddvvkivnlackynlciipigggts
vsyglmcpadetrtiisldtsqmnrilwvdennltahveagitgqelerqlkesgyctgh
epdslefstvggwistrasgmkkniygniedlvvhmkvvtprgviekscqgprmstgpdi
hhfimgsegtlgviteatikirptpeyqkygsvafpnfeqgvaclreiakqrcapasirl
mdnqqfqfghalkpqvssiftsfldglkkfyitkfkgfdpnqlsvatllfegdrekvlqh
ekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyiigesfetsapwdrvvdl
crnvkerirreckekgvqfpplstcrvtqtydagaciyfyfafnyrgisdplavfeqtea
aareeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkdyvdptnifgnrnll

    Sequence, based on observed residues (ATOM records):
    >6gouC (C:)
giipkkrqelmkwngwgyndskfflnkkgqleltgkryplsgvalptfkdwiqntfgint
ppsivnedflhelkktnisysqeaddrvfrahghclheifllregmferipdivlwptch
ddvvkivnlackynlciipigggtsvsyglmcpadetrtiisldtsqmnrilwvdennlt
ahveagitgqelerqlkesgyctghepdslefstvggwistrasgmkkniygniedlvvh
mkvvtprgviekscqgprmstgpdihhfimgsegtlgviteatikirptpeyqkygsvaf
pnfeqgvaclreiakqrcapasirlmdnqqfqfghalkpdpnqlsvatllfegdrekvlq
hekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyiigesfetsapwdrvvd
lcrnvkerirreckekgvlstcrvtqtydagaciyfyfafnyrgisdplavfeqteaaar
eeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkdyvdptnifgnrnll

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gouD (D:)
maeaaaaaaaaaaagetsassgsaaerdpdqdragrrlrvlsghllgrpqealstnecka
rraasaataaptatpaapesgiipkkrqelmkwngwgyndskfflnkkgqleltgkrypl
sgvalptfkdwiqntfginldhkttskaslnpsdtppsivnedflhelkktnisysqead
drvfrahghclheifllregmferipdivlwptchddvvkivnlackynlciipigggts
vsyglmcpadetrtiisldtsqmnrilwvdennltahveagitgqelerqlkesgyctgh
epdslefstvggwistrasgmkkniygniedlvvhmkvvtprgviekscqgprmstgpdi
hhfimgsegtlgviteatikirptpeyqkygsvafpnfeqgvaclreiakqrcapasirl
mdnqqfqfghalkpqvssiftsfldglkkfyitkfkgfdpnqlsvatllfegdrekvlqh
ekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyiigesfetsapwdrvvdl
crnvkerirreckekgvqfpplstcrvtqtydagaciyfyfafnyrgisdplavfeqtea
aareeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkdyvdptnifgnrnll

    Sequence, based on observed residues (ATOM records):
    >6gouD (D:)
giipkkrqelmkwngwgyndskfflnkkgqleltgkryplsgvalptfkdwiqntfginl
tppsivnedflhelkktnisysqeaddrvfrahghclheifllregmferipdivlwptc
hddvvkivnlackynlciipigggtsvsyglmcpadetrtiisldtsqmnrilwvdennl
tahveagitgqelerqlkesgyctghepdslefstvggwistrasgmkkniygniedlvv
hmkvvtprgviekscqgprmstgpdihhfimgsegtlgviteatikirptpeyqkygsva
fpnfeqgvaclreiakqrcapasirlmdnqqfqfghalkpdpnqlsvatllfegdrekvl
qhekqvydiaakfgglaagedngqrgylltyviaymrdlgleyyiigesfetsapwdrvv
dlcrnvkerirreckekgvqfpplstcrvtqtydagaciyfyfafnyrgisdplavfeqt
eaaareeilanggslshhhgvgklrkqwlkesisdvgfgmlksvkdyvdptnifgnrnll