PDB entry 6glw

View 6glw on RCSB PDB site
Description: Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11
Class: sugar binding protein
Keywords: Fab, galectin-10, autocrystallizing, crystal solubilisation, SUGAR BINDING PROTEIN
Deposited on 2018-05-23, released 2019-06-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-05, with a file datestamp of 2019-05-30.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Galectin-10
    Species: Homo sapiens [TaxId:9606]
    Gene: CLC, LGALS10, LGALS10A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6glwa_
  • Chain 'B':
    Compound: Galectin-10
    Species: Homo sapiens [TaxId:9606]
    Gene: CLC, LGALS10, LGALS10A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6glwb_
  • Chain 'C':
    Compound: Fab 1D11 - Heavy chain
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GLW (0-End)
    Domains in SCOPe 2.08: d6glwc_
  • Chain 'D':
    Compound: Fab 1D11 - Light chain
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GLW
    Domains in SCOPe 2.08: d6glwd1, d6glwd2
  • Chain 'H':
    Compound: Fab 1D11 - Heavy chain
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GLW (0-229)
    Domains in SCOPe 2.08: d6glwh_
  • Chain 'L':
    Compound: Fab 1D11 - Light chain
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GLW (0-215)
    Domains in SCOPe 2.08: d6glwl1, d6glwl2
  • Heterogens: PG4, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6glwA (A:)
mastthhhhhhdtdipttgggsrpddddkenlyfqghmsllpvpyteaaslstgstvtik
grplacflnepylqvdfhtemkeesdivfhfqvcfgrrvvmnsreygawkqqvesknmpf
qdgqefelsisvlpdkyqvmvngqssytfdhrikpeavkmvqvwrdisltkfnvsylkr

    Sequence, based on observed residues (ATOM records): (download) 
    >6glwA (A:)
sllpvpyteaaslstgstvtikgrplacflnepylqvdfhtemkeesdivfhfqvcfgrr
vvmnsreygawkqqvesknmpfqdgqefelsisvlpdkyqvmvngqssytfdhrikpeav
kmvqvwrdisltkfnvsyl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6glwB (B:)
mastthhhhhhdtdipttgggsrpddddkenlyfqghmsllpvpyteaaslstgstvtik
grplacflnepylqvdfhtemkeesdivfhfqvcfgrrvvmnsreygawkqqvesknmpf
qdgqefelsisvlpdkyqvmvngqssytfdhrikpeavkmvqvwrdisltkfnvsylkr

    Sequence, based on observed residues (ATOM records): (download) 
    >6glwB (B:)
msllpvpyteaaslstgstvtikgrplacflnepylqvdfhtemkeesdivfhfqvcfgr
rvvmnsreygawkqqvesknmpfqdgqefelsisvlpdkyqvmvngqssytfdhrikpea
vkmvqvwrdisltkfnvsy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6glwC (C:)
qvqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewvsgiswnggstyy
aesmkgrftisrdnakntlylqmnslksedtavyycakdrnlgyrlgypydywgqgtqvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >6glwC (C:)
qvqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewvsgiswnggstyy
aesmkgrftisrdnakntlylqmnslksedtavyycakdrnlgyrlgypydywgqgtqvt
vssastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6glwD (D:)
qsvltqppsvsgspgetvtiscagtssdvgygnyvswyqqlpgmaprlliyevnkrasgi
tdrfsgsksgntasltisglqsedegdyycasyrssnnavfgggthltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6glwD (D:)
svltqppsvsgspgetvtiscagtssdvgygnyvswyqqlpgmaprlliyevnkrasgit
drfsgsksgntasltisglqsedegdyycasyrssnnavfgggthltvlgqpkaapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapte

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6glwH (H:)
qvqlvesggglvqpggslrlscaasgftfddyamswvrqapgkglewvsgiswnggstyy
aesmkgrftisrdnakntlylqmnslksedtavyycakdrnlgyrlgypydywgqgtqvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6glwL (L:)
qsvltqppsvsgspgetvtiscagtssdvgygnyvswyqqlpgmaprlliyevnkrasgi
tdrfsgsksgntasltisglqsedegdyycasyrssnnavfgggthltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs