PDB entry 6glt

View 6glt on RCSB PDB site
Description: Crystal structure of hMTH1 D120N in the presence of acetate
Class: hydrolase
Keywords: Hydrolase, DNA repair
Deposited on 2018-05-23, released 2019-02-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-20, with a file datestamp of 2019-02-15.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 7,8-dihydro-8-oxoguanine triphosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: NUDT1, MTH1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36639 (Start-181)
      • engineered mutation (145)
    Domains in SCOPe 2.08: d6glta_
  • Heterogens: DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6gltA (A:)
mkhhhhhhpmsdydipttenlyfqgamgasrlytlvlvlqpqrvllgmkkrgfgagrwng
fggkvqegetiedgarrelqeesgltvdalhkvgqivfefvgepelmdvhvfctdsiqgt
pvesdemrpcwfqldqipfkdmwpdnsywfplllqkkkfhgyfkfqgqdtildytlrevd
tv

    Sequence, based on observed residues (ATOM records): (download) 
    >6gltA (A:)
asrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesgltvd
alhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpdnsy
wfplllqkkkfhgyfkfqgqdtildytlrevdtv