PDB entry 6glh
View 6glh on RCSB PDB site
Description: Crystal structure of hMTH1 F27A in complex with LW14 in the absence of acetate
Class: hydrolase
Keywords: Inhibitor, Complex, Hydrolase, DNA repair, Fragment
Deposited on
2018-05-23, released
2019-02-20
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-02-20, with a file datestamp of
2019-02-15.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: N/A
AEROSPACI score: 0.66
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 7,8-dihydro-8-oxoguanine triphosphatase
Species: Homo sapiens [TaxId:9606]
Gene: NUDT1, MTH1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6glha_ - Heterogens: BU8, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6glhA (A:)
mkhhhhhhpmsdydipttenlyfqgamgasrlytlvlvlqpqrvllgmkkrgagagrwng
fggkvqegetiedgarrelqeesgltvdalhkvgqivfefvgepelmdvhvfctdsiqgt
pvesdemrpcwfqldqipfkdmwpddsywfplllqkkkfhgyfkfqgqdtildytlrevd
tv
Sequence, based on observed residues (ATOM records): (download)
>6glhA (A:)
asrlytlvlvlqpqrvllgmkkrgagagrwngfggkvqegetiedgarrelqeesgltvd
alhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpddsy
wfplllqkkkfhgyfkfqgqdtildytlrevdtv