PDB entry 6gl7

View 6gl7 on RCSB PDB site
Description: neurturin-gfra2-ret extracellular complex
Deposited on 2018-05-23, released 2019-08-14
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 6.3 Å
R-factor: N/A
AEROSPACI score: -0.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neurturin
    Species: Homo sapiens [TaxId:9606]
    Gene: NRTN
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Neurturin
    Species: Homo sapiens [TaxId:9606]
    Gene: NRTN
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: GDNF family receptor alpha-2
    Species: Homo sapiens [TaxId:9606]
    Gene: GFRA2, GDNFRB, RETL2, TRNR2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: GDNF family receptor alpha-2
    Species: Homo sapiens [TaxId:9606]
    Gene: GFRA2, GDNFRB, RETL2, TRNR2
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: proto-oncogene tyrosine-protein kinase receptor ret
    Species: Homo sapiens [TaxId:9606]
    Gene: RET, CDHF12, CDHR16, PTC, RET51
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: proto-oncogene tyrosine-protein kinase receptor ret
    Species: Homo sapiens [TaxId:9606]
    Gene: RET, CDHF12, CDHR16, PTC, RET51
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gl7A (A:)
arlgarpcglrelevrvselglgyasdetvlfrycagaceaaarvydlglrrlrqrrrlr
rervraqpccrptayedevsfldahsryhtvhelsarecacv

    Sequence, based on observed residues (ATOM records):
    >6gl7A (A:)
lgarpcglrelevrvselglgyasdetvlfrycagaceaaarvydlglrrlrqrrrlrre
rvraqpccrptayedevsfldahsryhtvhelsarecacv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gl7B (B:)
arlgarpcglrelevrvselglgyasdetvlfrycagaceaaarvydlglrrlrqrrrlr
rervraqpccrptayedevsfldahsryhtvhelsarecacv

    Sequence, based on observed residues (ATOM records):
    >6gl7B (B:)
lgarpcglrelevrvselglgyasdetvlfrycagaceaaarvydlglrrlrqrrrlrre
rvraqpccrptayedevsfldahsryhtvhelsarecacv

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gl7C (C:)
spsslqgpelhgwrppvdcvranelcaaesncssryrtlrqclagrdrntmlankecqaa
levlqesplydcrckrgmkkelqclqiywsihlgltegeefyeaspyepvtsrlsdifrl
asifsgtgadpvvsaksnhcldaakacnlndnckklrssyisicnreisptercnrrkch
kalrqffdrvpseytyrmlfcscqdqacaerrrqtilpscsyedkekpncldlrgvcrtd
hlcrsrladfhancrasyqtvtscpadnyqaclgsyagmigfdmtpnyvdssptgivvsp
wcscrgsgnmeeecekflrdftenpclrnaiqafgngtdvnvspkgpsfqatqaprvekt
pslpddlsdstslgtsvittctsvqeqglkannskelsmcftelttniipgsnkvikpns
hhhhhh

    Sequence, based on observed residues (ATOM records):
    >6gl7C (C:)
dcvranelcaaesncssryrtlrqclankecqaalevlqesplydcrckrgmkkelqclq
iywsihlgefyeaspyepvtsrlsdifrlasifsgsnhcldaakacnlndnckklrssyi
sicnreisptercnrrkchkalrqffdrvpseytyrmlfcscqdqacaerrrqtilpscs
yedkekpncldlrgvcrtdhlcrsrladfhancrasyqtvtscpadnyqaclgsyagmig
fdmtpnyvdssptgivvspwcscrgsgnmeeecekflrdftenpclrnaiqafgngt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gl7D (D:)
spsslqgpelhgwrppvdcvranelcaaesncssryrtlrqclagrdrntmlankecqaa
levlqesplydcrckrgmkkelqclqiywsihlgltegeefyeaspyepvtsrlsdifrl
asifsgtgadpvvsaksnhcldaakacnlndnckklrssyisicnreisptercnrrkch
kalrqffdrvpseytyrmlfcscqdqacaerrrqtilpscsyedkekpncldlrgvcrtd
hlcrsrladfhancrasyqtvtscpadnyqaclgsyagmigfdmtpnyvdssptgivvsp
wcscrgsgnmeeecekflrdftenpclrnaiqafgngtdvnvspkgpsfqatqaprvekt
pslpddlsdstslgtsvittctsvqeqglkannskelsmcftelttniipgsnkvikpns
hhhhhh

    Sequence, based on observed residues (ATOM records):
    >6gl7D (D:)
dcvranelcaaesncssryrtlrqclankecqaalevlqesplydcrckrgmkkelqclq
iywsihlgefyeaspyepvtsrlsdifrlasifsgsnhcldaakacnlndnckklrssyi
sicnreisptercnrrkchkalrqffdrvpseytyrmlfcscqdqacaerrrqtilpscs
yedkekpncldlrgvcrtdhlcrsrladfhancrasyqtvtscpadnyqaclgsyagmig
fdmtpnyvdssptgivvspwcscrgsgnmeeecekflrdftenpclrnaiqafgngt

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6gl7E (E:)
lyfsrdayweklyvdqaagtpllyvhalrdapeevpsfrlgqhlygtyrtrlhennwici
qedtgllylnrsldhssweklsvrnrgfplltvylkvflsptslregecqwpgcarvyfs
ffntsfpacsslkprelcfpetrpsfrirenrppgtfhqfrllpvqflcpnisvayrlle
geglpfrcapdslevstrwaldreqrekyelvavctvhagareevvmvpfpvtvydedds
aptfpagvdtasavvefkrkedtvvatlrvfdadvvpasgelvrrytstllpgdtwaqqt
frvehwpnetsvqangsfvratvhdyrlvlnrnlsisenrtmqlavlvndsdfqgpgagv
lllhfnvsvlpvslhlpstyslsvsrrarrfaqigkvcvencqafsginvqyklhssgan
cstlgvvtsaedtsgilfvndtkalrrpkcaelhymvvatdqqtsrqaqaqllvtvegsy
vaeeagcplscavskrrleceecgglgsptgrcewrqgdgkgitrnfstcspstktcpdg
hcdvvetqdinicpqdclrgsivgghepgeprgikagygtcncfpeeekcfcepediqdp
lcdelcrenlyfq

    Sequence, based on observed residues (ATOM records):
    >6gl7E (E:)
lyfsrdayweklyvdqaagtpllyvhalrdapeevpsfrlgqhlygtyrtrlhennwici
qedtgllylnrsldhssweklsvrnrgfplltvylkvflsptegecqwpgcarvyfsffn
tsfpacsslkprelcfpetrpsfrirenrppgtfhqfrllpvqflcpnisvayrllegeg
lpfrcapdslevstrwaldreqrekyelvavctvhreevvmvpfpvtvydeddsaptfpa
gvdtasavvefkrkedtvvatlrvfdadvvpasgelvrrytstllpgdtwaqqtfrvehw
pnetsvqangsfvratvhdyrlvlnrnlsisenrtmqlavlvnpvslhlpstyslsvsrr
arrfaqigkvcvencqafsginvqyklhssgancstlgvvtsaedtsgilfvndtkalrr
pkcaelhymvvatdqqtsrqaqaqllvtve

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6gl7F (F:)
lyfsrdayweklyvdqaagtpllyvhalrdapeevpsfrlgqhlygtyrtrlhennwici
qedtgllylnrsldhssweklsvrnrgfplltvylkvflsptslregecqwpgcarvyfs
ffntsfpacsslkprelcfpetrpsfrirenrppgtfhqfrllpvqflcpnisvayrlle
geglpfrcapdslevstrwaldreqrekyelvavctvhagareevvmvpfpvtvydedds
aptfpagvdtasavvefkrkedtvvatlrvfdadvvpasgelvrrytstllpgdtwaqqt
frvehwpnetsvqangsfvratvhdyrlvlnrnlsisenrtmqlavlvndsdfqgpgagv
lllhfnvsvlpvslhlpstyslsvsrrarrfaqigkvcvencqafsginvqyklhssgan
cstlgvvtsaedtsgilfvndtkalrrpkcaelhymvvatdqqtsrqaqaqllvtvegsy
vaeeagcplscavskrrleceecgglgsptgrcewrqgdgkgitrnfstcspstktcpdg
hcdvvetqdinicpqdclrgsivgghepgeprgikagygtcncfpeeekcfcepediqdp
lcdelcrenlyfq

    Sequence, based on observed residues (ATOM records):
    >6gl7F (F:)
lyfsrdayweklyvdqaagtpllyvhalrdapeevpsfrlgqhlygtyrtrlhennwici
qedtgllylnrsldhssweklsvrnrgfplltvylkvflsptegecqwpgcarvyfsffn
tsfpacsslkprelcfpetrpsfrirenrppgtfhqfrllpvqflcpnisvayrllegeg
lpfrcapdslevstrwaldreqrekyelvavctvhreevvmvpfpvtvydeddsaptfpa
gvdtasavvefkrkedtvvatlrvfdadvvpasgelvrrytstllpgdtwaqqtfrvehw
pnetsvqangsfvratvhdyrlvlnrnlsisenrtmqlavlvnpvslhlpstyslsvsrr
arrfaqigkvcvencqafsginvqyklhssgancstlgvvtsaedtsgilfvndtkalrr
pkcaelhymvvatdqqtsrqaqaqllvtve