PDB entry 6gkf

View 6gkf on RCSB PDB site
Description: structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif ser139
Deposited on 2018-05-20, released 2018-10-17
The last revision was dated 2018-11-28, with a file datestamp of 2018-11-23.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: 14-3-3 protein gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: YWHAG
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF (0-7)
  • Chain 'J':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF (0-End)
  • Chain 'K':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF (0-7)
  • Chain 'L':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF
  • Chain 'M':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF (0-7)
  • Chain 'N':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF
  • Chain 'O':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF (0-7)
  • Chain 'P':
    Compound: Caspase-2
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GKF (0-7)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gkfA (A:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfA (A:)
dreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswrv
issieqktnekkiemvrayrekiekeleavcqdvlslldnylikqyeskvfylkmkgdyy
rylaevatgekratvvessekayseaheiskehmqpthpirlglalnysvfyyeiqnape
qachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gkfB (B:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfB (B:)
vdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswr
vissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnyliqyeskvfylkmk
gdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnysvfyyeiq
napeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gkfC (C:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfC (C:)
vdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswr
vissieqktsadekkiemvrayrekiekeleavcqdvlslldnylisetqyeskvfylkm
kgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnysvfyyei
qnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gkfD (D:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfD (D:)
vdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswr
vissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsqyeskvfy
lkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnysvfy
yeiqnapeqachlaktafddaiaeldtlykdstlimqllrdnltlwt

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6gkfE (E:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfE (E:)
vdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswr
vissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyeskv
fylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnysv
fyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6gkfF (F:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfF (F:)
vdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswr
vissieqktsekkiemvrayrekiekeleavcqdvlslldnylikqyeskvfylkmkgdy
yrylaevatgekratvvessekayseaheiskehpthpirlglalnysvfyyeiqnapeq
achlaktafddaiaesykdstlimqllrdnltl

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6gkfG (G:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfG (G:)
vdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswr
vissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnyliktqyeskvfylk
mkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnysvfyye
iqnapeqachlaktafddaiaetlimqllrdnltlwt

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6gkfH (H:)
mvdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrssw
rvissieqktsadgnekkiemvrayrekiekeleavcqdvlslldnylikncsetqyesk
vfylkmkgdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnys
vfyyeiqnapeqachlaktafddaiaeldtlnedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6gkfH (H:)
vdreqlvqkarlaeqaeryddmaaamknvtelneplsneernllsvayknvvgarrsswr
vissieqktkkiemvrayrekiekeleavcqdvlslldnylikncsetqyeskvfylkmk
gdyyrylaevatgekratvvessekayseaheiskehmqpthpirlglalnysvfyyeiq
napeqachlaktafddaiaelykdstlimqllrdnltlwt

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >6gkfI (I:)
ydlslpfp

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6gkfJ (J:)
ydlslpfp

    Sequence, based on observed residues (ATOM records):
    >6gkfJ (J:)
ydlslpf

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records:
    >6gkfK (K:)
ydlslpfp

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6gkfL (L:)
ydlslpfp

    Sequence, based on observed residues (ATOM records):
    >6gkfL (L:)
dlslpf

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records:
    >6gkfM (M:)
ydlslpfp

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6gkfN (N:)
ydlslpfp

    Sequence, based on observed residues (ATOM records):
    >6gkfN (N:)
dlslpf

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records:
    >6gkfO (O:)
ydlslpfp

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records:
    >6gkfP (P:)
ydlslpfp