PDB entry 6gk9

View 6gk9 on RCSB PDB site
Description: inhibited structure of impdh from pseudomonas aeruginosa
Deposited on 2018-05-18, released 2019-02-27
The last revision was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 2.54 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HXM5 (20-End)
      • expression tag (19)
  • Chain 'B':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HXM5 (20-End)
      • expression tag (19)
  • Chain 'G':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Pseudomonas aeruginosa PAO1 [TaxId:208964]
    Gene: guaB, PA3770
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HXM5 (20-End)
      • expression tag (19)
  • Heterogens: F2K, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gk9A (A:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9A (A:)
hmlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlai
amaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtvtpstkiiellqmareygfs
gfpvveqgelvgivtgrdlrdtvaaimtpkdklvtaregtpleemkaklyenriekmlvv
denfylrglvtfrdiekaktyplaskdeqgrlrvgaavgtgadtgervaalvaagvdvvv
vdtahghskgviervrwvkqtfpdvqviggniataeaakalaeagadavkvgigpgsctt
rivagvgvpqisaianvaaalegtgvpliadggirfsgdlakamvagaycvmmgsmfagt
eeapgeielfqgrsyksyrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpqfvr
itga

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gk9B (B:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9B (B:)
mlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlaia
maqeggigiihknmgieqqaaevrkvkkhetaivrdpvtvtpstkiiellqmareygfsg
fpvveqgelvgivtgrdlrvdtvaaimtpkdklvtaregtpleemkaklyenriekmlvv
denfylrglvtfrdiekaktyplaskdeqgrlrvgaavgtgadtgervaalvaagvdvvv
vdtahghskgviervrwvkqtfpdvqviggniataeaakalaeagadavkvgigpgsict
trivagvgvpqisaianvaaalegtgvpliadggirfsgdlakamvagaycvmmgsmfag
teeapgeielfqgrsyksyrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpqfv
ritg

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gk9C (C:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9C (C:)
mlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlaia
maqeggigiihknmgieqqaaevrkvkkhetaivrdpvtiellqmareygftgrdlmtpk
dklvtgtpleemkaklyenriekmllvtfrdiekaktyplaskdeqgrlrvgaavgtgad
tgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniataeaakalae
agadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggirfsgdlak
amvagaycvmmgsmfagteeapgeielfqgrsyksyvpykgalsaivhqlmgglraamgy
tgsadiqqmrtqpqfvritga

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gk9D (D:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9D (D:)
mlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlaia
maqeggigiihknmgieqqaaevrkvkkhetaivrdpvtvtpstkiiellqmareygfsg
fpvveqgelvgivtgrdlrdtvaaimtpkdklvtaregtpleemkaklyenriekmlvvd
enfylrglvtfrdiekaktyplaskdeqgrlrvgaavgtgadtgervaalvaagvdvvvv
dtahghskgviervrwvkqtfpdvqviggniataeaakalaeagadavkvgigpgsictt
rivagvgvpqisaianvaaalegtgvpliadggirfsgdlakamvagaycvmmgsmfagt
eeapgeielfqgrsyksygrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpqfv
ritg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6gk9E (E:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9E (E:)
mlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlaia
maqeggigiihknmgieqqaaevrkvkkhetaivrdpvtvtpstkiiellqmareygfsg
fpvveqgelvgivtgrdlrdtvaaimtpkdklvtaregtpleemkaklyenriekmlvvd
enfylrglvtfrdiekaktyplaskdeqgrlrvgaavgtgadtgervaalvaagvdvvvv
dtahghskgviervrwvkqtfpdvqviggniataeaakalaeagadavkvgigpgsictt
rivagvgvpqisaianvaaalegtgvpliadggirfsgdlakamvagaycvmmgsmfagt
eeapgeielfqgrsyksyrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpqfvr
itga

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6gk9F (F:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9F (F:)
hmlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlai
amaqeggigiihknmgieqqaaevrkvkkhettyplaskdeqgrlrvgaavgtgadtger
vaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniataeaakalaeagad
avkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggirfsgdlakamva
gaycvmmgsmfagteeapgeielfqgrsyksyrvpykgalsaivhqlmgglraamgytgs
adiqqmrtqpqfvritg

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6gk9G (G:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9G (G:)
mlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlaia
maqeggigiihknmgieqqaaevrkvkkhetaivrtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrvpykgalsaivhqlm
gglraamgytgsadiqqmrtqpqfvritg

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6gk9H (H:)
mgsshhhhhhssglvprgshmlrisqealtfddvllipgysevlpkdvslktrltrgiel
niplvsaamdtvtearlaiamaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtv
tpstkiiellqmareygfsgfpvveqgelvgivtgrdlrvkpnagdtvaaimtpkdklvt
aregtpleemkaklyenriekmlvvdenfylrglvtfrdiekaktyplaskdeqgrlrvg
aavgtgadtgervaalvaagvdvvvvdtahghskgviervrwvkqtfpdvqviggniata
eaakalaeagadavkvgigpgsicttrivagvgvpqisaianvaaalegtgvpliadggi
rfsgdlakamvagaycvmmgsmfagteeapgeielfqgrsyksyrgmgslgamsgsqgss
dryfqdasagaeklvpegiegrvpykgalsaivhqlmgglraamgytgsadiqqmrtqpq
fvritgagmaeshvhdvqitkeapnyrvg

    Sequence, based on observed residues (ATOM records):
    >6gk9H (H:)
hmlrisqealtfddvllipgysevlpkdvslktrltrgielniplvsaamdtvtearlai
amaqeggigiihknmgieqqaaevrkvkkhetaivrdpvtvtpstkiiellqmareygfs
gfpvveqgelvgivtgrdlrdtvaaimtpkdklvtaregtpleemkaklyenriekmlvv
lrglvtfrdiekaktyplaskdeqgrlrvgaavgtgadtgervaalvaagvdvvvvdtah
ghskgviervrwvkqtfpdvqviggniataeaakalaeagadavkvgigpgsicttriva
gvgvpqisaianvaaalegtgvpliadggirfsgdlakamvagaycvmmgsmfagteeap
geielfqgrsyksyvpykgalsaivhqlmgglraamgytgsadiqqmrtqpqfvritga