PDB entry 6gjg

View 6gjg on RCSB PDB site
Description: plasmodium falciparum dihydroorotate dehydrogenase dhodh in complex with 3,6-dimethyl-n-(4-(trifluoromethyl)phenyl)-(1,2)oxazolo(5,4-d) pyrimidin-4-amine
Deposited on 2018-05-16, released 2018-09-19
The last revision was dated 2018-09-19, with a file datestamp of 2018-09-14.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydroorotate dehydrogenase (quinone), mitochondrial
    Species: Plasmodium falciparum [TaxId:36329]
    Gene: PFF0160c
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Dihydroorotate dehydrogenase (quinone), mitochondrial
    Species: Plasmodium falciparum [TaxId:36329]
    Gene: PFF0160c
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ORO, FMN, F1T, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gjgA (A:)
mghhhhhhaenlyfqgadpfesynpefflydiflkfclkyidgeichdlflllgkynilp
ydtsndsiyactnikhldfinpfgvaagfdkngvcidsilklgfsfieigtitprgqtgn
akprifrdvesrsiinscgfnnmgcdkvtenlilfrkrqeedkllskhivgvsigknkdt
vnivddlkycinkigryadyiainvsspntpglrdnqeagklkniilsvkeeidnleknn
imndeflwfnttkkkplvfvklapdlnqeqkkeiadvlletnidgmiisntttqindiks
fenkkggvsgaklkdistkficemynytnkqipiiasggifsgldalekieagasvcqly
sclvfngmksavqikrelnhllyqrgyynlkeaigrkhsks

    Sequence, based on observed residues (ATOM records):
    >6gjgA (A:)
npefflydiflkfclkyidgeichdlflllgkynilpydtsndsiyactnikhldfinpf
gvaagfdkngvcidsilklgfsfieigtitprgqtgnakprifrdvesrsiinscgfnnm
gcdkvtenlilfrkrqeedkllskhivgvsigknkdtvnivddlkycinkigryadyiai
nvsspntpglrdnqeagklkniilsvkeeidnleknnflwfnttkkkplvfvklapdlnq
eqkkeiadvlletnidgmiisntttqindiksfenkkggvsgaklkdistkficemynyt
nkqipiiasggifsgldalekieagasvcqlysclvfngmksavqikrelnhllyqrgyy
nlkeaigrkhs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gjgB (B:)
mghhhhhhaenlyfqgadpfesynpefflydiflkfclkyidgeichdlflllgkynilp
ydtsndsiyactnikhldfinpfgvaagfdkngvcidsilklgfsfieigtitprgqtgn
akprifrdvesrsiinscgfnnmgcdkvtenlilfrkrqeedkllskhivgvsigknkdt
vnivddlkycinkigryadyiainvsspntpglrdnqeagklkniilsvkeeidnleknn
imndeflwfnttkkkplvfvklapdlnqeqkkeiadvlletnidgmiisntttqindiks
fenkkggvsgaklkdistkficemynytnkqipiiasggifsgldalekieagasvcqly
sclvfngmksavqikrelnhllyqrgyynlkeaigrkhsks

    Sequence, based on observed residues (ATOM records):
    >6gjgB (B:)
npefflydiflkfclkyidgeichdlflllgkynilpydtsndsiyactnikhldfinpf
gvaagfdkngvcidsilklgfsfieigtitprgqtgnakprifrdvesrsiinscgfnnm
gcdkvtenlilfrkrqeedkllskhivgvsigknkdtvnivddlkycinkigryadyiai
nvsspntpglrdnqeagklkniilsvkeeidnleknndeflwfnttkkkplvfvklapdl
nqeqkkeiadvlletnidgmiisntttqindiksfenkkggvsgaklkdistkficemyn
ytnkqipiiasggifsgldalekieagasvcqlysclvfngmksavqikrelnhllyqrg
yynlkeaigrkhs