PDB entry 6ghk

View 6ghk on RCSB PDB site
Description: human parp1 (artd1) - catalytic domain in complex with inhibitor me0527
Deposited on 2018-05-08, released 2019-05-22
The last revision was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Poly [ADP-ribose] polymerase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP1, ADPRT, PPOL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09874 (1-351)
      • initiating methionine (0)
      • conflict (101)
      • expression tag (351-354)
  • Chain 'B':
    Compound: Poly [ADP-ribose] polymerase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP1, ADPRT, PPOL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09874 (1-351)
      • initiating methionine (0)
      • conflict (101)
      • expression tag (351-356)
  • Heterogens: EZ2, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ghkA (A:)
mksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqav
sqgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrg
gsddsskdpidvnyeklktdikvvdrdseeaeiirkyvknthatthnaydlevidifkie
regecqrykpfkqlhnrrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadm
vsksanychtsqgdpiglillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsa
nisldgvdvplgtgissgvndtsllyneyivydiaqvnlkyllklkfnfktahhhhhh

    Sequence, based on observed residues (ATOM records):
    >6ghkA (A:)
mksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqav
sqgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrg
gssskdpidvnyeklktdikvvdrdseeaeiirkyvknthanaydlevidifkieregec
qrykpfkqlhnrrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadmvsksa
nychtsqgdpiglillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsanisld
gvdvplgtgissgvndtsllyneyivydiaqvnlkyllklkfnfktahhh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ghkB (B:)
mksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqav
sqgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrg
gsddsskdpidvnyeklktdikvvdrdseeaeiirkyvknthatthnaydlevidifkie
regecqrykpfkqlhnrrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadm
vsksanychtsqgdpiglillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsa
nisldgvdvplgtgissgvndtsllyneyivydiaqvnlkyllklkfnfktahhhhhh

    Sequence, based on observed residues (ATOM records):
    >6ghkB (B:)
mksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqav
sqgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrg
gssskdpidvnyeklktdikvvdrdseeaeiirkyvknthatthnaydlevidifkiere
gecqrykpfkqlhnrrllwhgsrttnfagilsqglriappeapvtgymfgkgiyfadmvs
ksanychtsqgdpiglillgevalgnmyelkhashisklpkgkhsvkglgkttpdpsani
sldgvdvplgtgissgvndtsllyneyivydiaqvnlkyllklkfnfktahhhhh