PDB entry 6ggh

View 6ggh on RCSB PDB site
Description: human jak1 kinase domain in complex with inhibitor
Deposited on 2018-05-03, released 2019-05-22
The last revision was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase JAK1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Tyrosine-protein kinase JAK1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EYQ, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gghA (A:)
tevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpesggnhiadl
kkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlk
yavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrd
spvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvt
rlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

    Sequence, based on observed residues (ATOM records):
    >6gghA (A:)
vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpesggnhiadlkk
eieilrnlyhenivkykgictngiklimeflpsgslkeylpknknkinlkqqlkyavqic
kgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfwy
apeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvntl
kegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gghB (B:)
tevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpesggnhiadl
kkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlk
yavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrd
spvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvt
rlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

    Sequence, based on observed residues (ATOM records):
    >6gghB (B:)
tevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslgnhiadlkkeie
ilrnlyhenivkykgictgiklimeflpsgslkeylpknknkinlkqqlkyavqickgmd
ylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfwyapec
lmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvntlkegk
rlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk