PDB entry 6gg6

View 6gg6 on RCSB PDB site
Description: crystal structure of m2 pyk in complex with serine.
Deposited on 2018-05-02, released 2018-05-23
The last revision was dated 2018-06-13, with a file datestamp of 2018-06-08.
Experiment type: XRAY
Resolution: 2.96 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Pyruvate kinase PKM
    Species: Homo sapiens [TaxId:9606]
    Gene: PKM, OIP3, PK2, PK3, PKM2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: K, MG, SER, PO4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gg6A (A:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6A (A:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gg6B (B:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6B (B:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gg6C (C:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6C (C:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gg6D (D:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6D (D:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6gg6E (E:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6E (E:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6gg6F (F:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6F (F:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6gg6G (G:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6G (G:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6gg6H (H:)
mgsshhhhhhssglvprgshmskphseagtafiqtqqlhaamadtflehmcrldidsppi
tarntgiictigpasrsvetlkemiksgmnvarlnfshgtheyhaetiknvrtatesfas
dpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlkitldnaymekcdenilwld
yknickvvevgskiyvddglislqvkqkgadflvtevenggslgskkgvnlpgaavdlpa
vsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgekgknikiiskienhegvrrf
deileasdgimvargdlgieipaekvflaqkmmigrcnragkpvicatqmlesmikkprp
traegsdvanavldgadcimlsgetakgdypleavrmqhliareaeaaiyhlqlfeelrr
lapitsdpteatavgaveasfkccsgaiivltksgrsahqvaryrprapiiavtrnpqta
rqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkargffkkgdvvivltgwrpgsg
ftntmrvvpvp

    Sequence, based on observed residues (ATOM records):
    >6gg6H (H:)
madtflehmcrldidsppitarntgiictigpasrsvetlkemiksgmnvarlnfshgth
eyhaetiknvrtatesfasdpilyrpvavaldtkgpeirtglikgsgtaevelkkgatlk
itldnaymekcdenilwldyknickvvevgskiyvddglislqvkqkgadflvtevengg
slgskkgvnlpgaavdlpavsekdiqdlkfgveqdvdmvfasfirkasdvhevrkvlgek
gknikiiskienhegvrrfdeileasdgimvargdlgieipaekvflaqkmmigrcnrag
kpvicatqmlesmikkprptraegsdvanavldgadcimlsgetakgdypleavrmqhli
areaeaaiyhlqlfeelrrlapitsdpteatavgaveasfkccsgaiivltksgrsahqv
aryrprapiiavtrnpqtarqahlyrgifpvlckdpvqeawaedvdlrvnfamnvgkarg
ffkkgdvvivltgwrpgsgftntmrvvpvp