PDB entry 6gfj

View 6gfj on RCSB PDB site
Description: structure of rip2 card domain fused to crystallisable mbp tag
Deposited on 2018-04-30, released 2019-03-13
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F8NYV9 (Start-370)
      • conflict (2)
      • conflict (239)
      • conflict (359)
      • conflict (362-363)
      • conflict (368-369)
      • linker (370)
    • Uniprot O43353 (371-End)
  • Chain 'B':
    Compound: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F8NYV9 (Start-370)
      • conflict (2)
      • conflict (239)
      • conflict (359)
      • conflict (362-363)
      • conflict (368-369)
      • linker (370)
    • Uniprot O43353 (371-End)
  • Chain 'C':
    Compound: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F8NYV9 (Start-370)
      • conflict (2)
      • conflict (239)
      • conflict (359)
      • conflict (362-363)
      • conflict (368-369)
      • linker (370)
    • Uniprot O43353 (371-End)
  • Chain 'D':
    Compound: Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0F8NYV9 (Start-370)
      • conflict (239)
      • conflict (359)
      • conflict (362-363)
      • conflict (368-369)
      • linker (370)
    • Uniprot O43353 (371-End)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gfjA (A:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsa
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvda
alaaaqtnaaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptr
tskvrqlldttdiqgeefakvivqklkdnkqmglqpypeilvvsrspslnllqnksm

    Sequence, based on observed residues (ATOM records):
    >6gfjA (A:)
ieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiif
wahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdl
lpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdv
gvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsavn
ygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplga
valksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdaal
aaaqtnaaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptrts
kvrqlldttdiqgeefakvivqklkdnkqmglqpype

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gfjB (B:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsa
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvda
alaaaqtnaaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptr
tskvrqlldttdiqgeefakvivqklkdnkqmglqpypeilvvsrspslnllqnksm

    Sequence, based on observed residues (ATOM records):
    >6gfjB (B:)
ieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiif
wahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdl
lpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdv
gvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsavn
ygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplga
valksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdaal
aaaqtnaaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptrts
kvrqlldttdiqgeefakvivqklkdnkqmglqpype

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gfjC (C:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsa
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvda
alaaaqtnaaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptr
tskvrqlldttdiqgeefakvivqklkdnkqmglqpypeilvvsrspslnllqnksm

    Sequence, based on observed residues (ATOM records):
    >6gfjC (C:)
ieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiif
wahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdl
lpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdv
gvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsavn
ygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplga
valksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdaal
aaaqtnaaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptrts
kvrqlldttdiqgeefakvivqklkdnkqmglqpyp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gfjD (D:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsa
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvda
alaaaqtnaaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptr
tskvrqlldttdiqgeefakvivqklkdnkqmglqpypeilvvsrspslnllqnksm

    Sequence, based on observed residues (ATOM records):
    >6gfjD (D:)
lviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiifwahdr
fggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdllpnpp
ktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdvgvdna
gakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsavnygvtv
lptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplgavalks
yeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdaalaaaqt
naaaiaqqwiqskredivnqmteaclnqsldallsrdlimkedyelvstkptrtskvrql
ldttdiqgeefakvivqklkdnkqmglqpype