PDB entry 6gev

View 6gev on RCSB PDB site
Description: Mineralocorticoid receptor in complex with (s)-13
Class: transcription
Keywords: Mineralocorticoid receptor, nuclear hormone receptor, steroid receptor, ligand complex, peptide complex, signaling protein, TRANSCRIPTION
Deposited on 2018-04-27, released 2019-01-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-09, with a file datestamp of 2019-01-04.
Experiment type: XRAY
Resolution: 1.54 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mineralocorticoid receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NR3C2, MCR, MLR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08235 (Start-271)
      • expression tag (18-19)
      • conflict (95)
      • conflict (97)
      • conflict (197)
    Domains in SCOPe 2.07: d6geva1, d6geva2
  • Chain 'B':
    Compound: Nuclear receptor coactivator 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOA1, BHLHE74, SRC1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GOL, EWN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6gevA (A:)
    mhnhnhnhnhnhnggenlyfqgtpspvmvleniepeivyagydsskpdtaenllstlnrl
    agkqmiqvvkwakvlpgfknlpledqitliqyswmsllsfalswrsykhtnsqflyfapd
    lvfneekmhqsamyelcqgmhqislqfvrlqltfeeytimkvllllstipkdglksqaaf
    eemrtnyikelrkmvtkspnnsgqswqrfyqltklldsmhdlvsdllefcfytfreshal
    kvefpamlveiisdqlpkvesgnakplyfhrkggslvprgsgggsggsggpqaqqksllq
    qllte
    

    Sequence, based on observed residues (ATOM records): (download)
    >6gevA (A:)
    yfspvmvleniepeivyagydsskpdtaenllstlnrlagkqmiqvvkwakvlpgfknlp
    ledqitliqyswmsllsfalswrsykhtnsqflyfapdlvfneekmhqsamyelcqgmhq
    islqfvrlqltfeeytimkvllllstipkdglksqaafeemrtnyikelrkmvtkspnns
    gqswqrfyqltklldsmhdlvsdllefcfytfreskvefpamlveiisdqlpkvesgnak
    plyfhrk
    

  • Chain 'B':
    No sequence available.